DxCodebookFY2027 · Oct 1, 2026 – Sep 30, 2027

Category · FY2027

C21 Malignant neoplasm of anus and anal canal

  • Header · not billable

C21 is not billable. The category heads 4 billable codes in FY2027: the 4 codes directly below it.

Index → code

  • Paget's diseaseextramammaryanus → C21.0
  • Carcinoma (malignant)cloacogenicunspecified site → C21.2
Billable codes
4
Subdivisions
4
CC / MCC codes
4 / 0
HCC V28 codes
4
New FY2027
0
Index entries
2

Codes in C21

  1. C21.0
    Malignant neoplasm of anus, unspecified
    BillableCC22
  2. C21.1
    Malignant neoplasm of anal canal
    BillableCC22
    Inclusion terms 1

    Inclusion terms

    • Malignant neoplasm of anal sphincter
  3. C21.2
    Malignant neoplasm of cloacogenic zone
    BillableCC22
  4. C21.8
    Malignant neoplasm of overlapping sites of rectum, anus and anal canal
    BillableCC22
    Inclusion terms 3

    Inclusion terms

    • Malignant neoplasm of anorectal junction
    • Malignant neoplasm of anorectum
    • Primary malignant neoplasm of two or more contiguous sites of rectum, anus and anal canal

CC/MCC: as a secondary diagnosis, unless the principal diagnosis is on the code’s PDX exclusion list (MS-DRG v44 Appendix C; list on the code card).

Sources of each column.

Instructions

At C21

Excludes2

  • malignant carcinoid tumors of the colon (C7A.02-) C7A.02
  • malignant melanoma of anal margin (C43.51) C43.51
  • malignant melanoma of anal skin (C43.51) C43.51
  • malignant melanoma of perianal skin (C43.51) C43.51
  • other and unspecified malignant neoplasm of anal margin (C44.500, C44.510, C44.520, C44.590) C44.500 C44.510 C44.520 C44.590
  • other and unspecified malignant neoplasm of anal skin (C44.500, C44.510, C44.520, C44.590) C44.500 C44.510 C44.520 C44.590
  • other and unspecified malignant neoplasm of perianal skin (C44.500, C44.510, C44.520, C44.590) C44.500 C44.510 C44.520 C44.590

Notes that also apply

Block C15-C26 instructions (Excludes1 1, Excludes2 1): printed on the block page.

Chapter 2 instructions (Notes 8): printed on the chapter 2 page.

Index entries

  • Paget's diseaseextramammaryanus → C21.0
  • Carcinoma (malignant)cloacogenicunspecified site → C21.2

NCHS Alphabetic Index. Index first, then the Tabular List.

Hierarchy