DxCodebookFY2027 · Oct 1, 2026 – Sep 30, 2027

Category · FY2027

C49 Malignant neoplasm of other connective and soft tissue

  • Header · not billable

C49 is not billable. The category heads 20 billable codes in FY2027, grouped under 10 subdivisions.

Index → code

  • Tumorstromalstomach → C49.A2
  • Tumorstromalgastrointestinal → C49.A-
  • Tumorstromalgastricmalignant → C49.A2

Where it sits

  1. Chapter 2 Neoplasms (C00-D49)
  2. C45-C49 Malignant neoplasms of mesothelial and soft tissue (C45-C49)
  3. C49 Malignant neoplasm of other connective and soft tissue
Billable codes
20
Subdivisions
10
CC / MCC codes
20 / 0
HCC V28 codes
20
New FY2027
0
Index entries
26

Codes in C49

  1. C49.0
    Malignant neoplasm of connective and soft tissue of head, face and neck
    BillableCC21
    Inclusion terms 2, Excludes1 1

    Inclusion terms

    • Malignant neoplasm of connective tissue of ear
    • Malignant neoplasm of connective tissue of eyelid

    Excludes1

    • connective tissue of orbit (C69.6-) C69.6
  2. C49.1
    Malignant neoplasm of connective and soft tissue of upper limb, including shoulder
    Header
  3. C49.10
    Malignant neoplasm of connective and soft tissue of unspecified upper limb, including shoulder
    BillableCC21
  4. C49.11
    Malignant neoplasm of connective and soft tissue of right upper limb, including shoulder
    BillableCC21
  5. C49.12
    Malignant neoplasm of connective and soft tissue of left upper limb, including shoulder
    BillableCC21
  6. C49.2
    Malignant neoplasm of connective and soft tissue of lower limb, including hip
    Header
  7. C49.20
    Malignant neoplasm of connective and soft tissue of unspecified lower limb, including hip
    BillableCC21
  8. C49.21
    Malignant neoplasm of connective and soft tissue of right lower limb, including hip
    BillableCC21
  9. C49.22
    Malignant neoplasm of connective and soft tissue of left lower limb, including hip
    BillableCC21
  10. C49.3
    Malignant neoplasm of connective and soft tissue of thorax
    BillableCC21
    Inclusion terms 3, Excludes1 4

    Inclusion terms

    • Malignant neoplasm of axilla
    • Malignant neoplasm of diaphragm
    • Malignant neoplasm of great vessels

    Excludes1

    • malignant neoplasm of breast (C50.-) C50
    • malignant neoplasm of heart (C38.0) C38.0
    • malignant neoplasm of mediastinum (C38.1-C38.3) C38.1 C38.3
    • malignant neoplasm of thymus (C37) C37
  11. C49.4
    Malignant neoplasm of connective and soft tissue of abdomen
    BillableCC23
    Inclusion terms 2

    Inclusion terms

    • Malignant neoplasm of abdominal wall
    • Malignant neoplasm of hypochondrium
  12. C49.5
    Malignant neoplasm of connective and soft tissue of pelvis
    BillableCC21
    Inclusion terms 3

    Inclusion terms

    • Malignant neoplasm of buttock
    • Malignant neoplasm of groin
    • Malignant neoplasm of perineum
  13. C49.6
    Malignant neoplasm of connective and soft tissue of trunk, unspecified
    BillableCC21
    Inclusion terms 1

    Inclusion terms

    • Malignant neoplasm of back NOS
  14. C49.8
    Malignant neoplasm of overlapping sites of connective and soft tissue
    BillableCC21
    Inclusion terms 1

    Inclusion terms

    • Primary malignant neoplasm of two or more contiguous sites of connective and soft tissue
  15. C49.9
    Malignant neoplasm of connective and soft tissue, unspecified
    BillableCC21
  16. C49.A
    Gastrointestinal stromal tumor
    Header
  17. C49.A0
    Gastrointestinal stromal tumor, unspecified site
    BillableCC23
  18. C49.A1
    Gastrointestinal stromal tumor of esophagus
    BillableCC23
  19. C49.A2
    Gastrointestinal stromal tumor of stomach
    BillableCC23
  20. C49.A3
    Gastrointestinal stromal tumor of small intestine
    BillableCC23
  21. C49.A4
    Gastrointestinal stromal tumor of large intestine
    BillableCC23
  22. C49.A5
    Gastrointestinal stromal tumor of rectum
    BillableCC23
  23. C49.A9
    Gastrointestinal stromal tumor of other sites
    BillableCC23

CC/MCC: as a secondary diagnosis, unless the principal diagnosis is on the code’s PDX exclusion list (MS-DRG v44 Appendix C; list on the code card).

Sources of each column.

Instructions

At C49

Includes

  • malignant neoplasm of blood vessel
  • malignant neoplasm of bursa
  • malignant neoplasm of cartilage
  • malignant neoplasm of fascia
  • malignant neoplasm of fat
  • malignant neoplasm of ligament, except uterine
  • malignant neoplasm of lymphatic vessel
  • malignant neoplasm of muscle
  • malignant neoplasm of synovia
  • malignant neoplasm of tendon (sheath)

Excludes1

  • malignant neoplasm of cartilage (of):
  • articular (C40-C41) C40 C41
  • larynx (C32.3) C32.3
  • nose (C30.0) C30.0
  • malignant neoplasm of connective tissue of breast (C50.-) C50

Excludes2

  • Kaposi's sarcoma of soft tissue (C46.1) C46.1
  • malignant neoplasm of heart (C38.0) C38.0
  • malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-) C47
  • malignant neoplasm of peritoneum (C48.2) C48.2
  • malignant neoplasm of retroperitoneum (C48.0) C48.0
  • malignant neoplasm of uterine ligament (C57.3) C57.3
  • mesothelioma (C45.-) C45

Notes that also apply

Chapter 2 instructions (Notes 8): printed on the chapter 2 page.

Index entries

  • Tumorstromalgastrointestinal → C49.A-
  • Tumorstromalstomach → C49.A2
  • Tumorstromalgastrointestinalmalignant → C49.A0
  • Tumorstromalgastrointestinalesophagus → C49.A1
  • Tumorstromalgastricmalignant → C49.A2
  • Tumorstromalgastrointestinalstomach → C49.A2
  • Tumorstromalstomachmalignant → C49.A2
  • Tumorstromalgastrointestinalsmall intestine → C49.A3
  • Tumorstromalgastrointestinallarge intestine → C49.A4
  • Tumorstromalgastrointestinalrectum → C49.A5
  • Tumorstromalgastrointestinalspecified site NEC → C49.A9
  • Tumorstromalgastrointestinalmalignantesophagus → C49.A1
  • Tumorstromalgastrointestinalmalignantstomach → C49.A2
  • Tumorstromalgastrointestinalmalignantduodenum → C49.A3
  • Tumorstromalgastrointestinalmalignantileum → C49.A3
  • Tumorstromalgastrointestinalmalignantjejunum → C49.A3
  • TumorstromalgastrointestinalmalignantMeckel diverticulum → C49.A3
  • Tumorstromalgastrointestinalmalignantsmall intestine → C49.A3
  • Tumorstromalintestinemalignantsmall → C49.A3
  • Tumorstromalgastrointestinalmalignantcolon → C49.A4
  • Tumorstromalgastrointestinalmalignantlarge intestine → C49.A4
  • Tumorstromalintestinemalignantlarge → C49.A4
  • Tumorstromalgastrointestinalmalignantrectum → C49.A5
  • Tumorstromalgastrointestinalmalignantomentum → C49.A9
  • Tumorstromalgastrointestinalmalignantperitoneum → C49.A9
  • Tumorstromalgastrointestinalmalignantspecified site NEC → C49.A9

NCHS Alphabetic Index. Index first, then the Tabular List.

Hierarchy