DxCodebookFY2027 · Oct 1, 2026 – Sep 30, 2027

Category · FY2027

D46 Myelodysplastic syndromes

  • Header · not billable

D46 is not billable. The category heads 11 billable codes in FY2027, grouped under 9 subdivisions.

Index → code

  • Myelodysplasia → D46.9
  • Preleukemia (syndrome) → D46.9
  • Myelodysplastic syndrome → D46.9

Where it sits

  1. Chapter 2 Neoplasms (C00-D49)
  2. D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)
  3. D46 Myelodysplastic syndromes
Billable codes
11
Subdivisions
9
CC / MCC codes
2 / 0
HCC V28 codes
11
New FY2027
0
Index entries
31

Codes in D46

  1. D46.0
    Refractory anemia without ring sideroblasts, so stated
    Billable19
    Inclusion terms 1

    Inclusion terms

    • Refractory anemia without sideroblasts, without excess of blasts
  2. D46.1
    Refractory anemia with ring sideroblasts
    Billable19
    Inclusion terms 1

    Inclusion terms

    • RARS
  3. D46.2
    Refractory anemia with excess of blasts [RAEB]
    Header
  4. D46.20
    Refractory anemia with excess of blasts, unspecified
    Billable19
    Inclusion terms 1

    Inclusion terms

    • RAEB NOS
  5. D46.21
    Refractory anemia with excess of blasts 1
    Billable19
    Inclusion terms 1

    Inclusion terms

    • RAEB 1
  6. D46.22
    Refractory anemia with excess of blasts 2
    BillableCC17
    Inclusion terms 1

    Inclusion terms

    • RAEB 2
  7. D46.A
    Refractory cytopenia with multilineage dysplasia
    Billable19
  8. D46.B
    Refractory cytopenia with multilineage dysplasia and ring sideroblasts
    Billable19
    Inclusion terms 1

    Inclusion terms

    • RCMD RS
  9. D46.C
    Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
    BillableCC19
    Inclusion terms 2

    Inclusion terms

    • Myelodysplastic syndrome with 5q deletion
    • 5q minus syndrome NOS
  10. D46.4
    Refractory anemia, unspecified
    Billable19
  11. D46.Z
    Other myelodysplastic syndromes
    Billable19
    Excludes1 1

    Excludes1

    • chronic myelomonocytic leukemia (C93.1-) C93.1
  12. D46.9
    Myelodysplastic syndrome, unspecified
    Billable19
    Inclusion terms 1

    Inclusion terms

    • Myelodysplasia NOS

CC/MCC: as a secondary diagnosis, unless the principal diagnosis is on the code’s PDX exclusion list (MS-DRG v44 Appendix C; list on the code card).

Sources of each column.

Instructions

At D46

Excludes2

  • drug-induced aplastic anemia (D61.1) D61.1

Use additional code

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) T36 T50

Notes that also apply

Block D37-D48 instructions (Notes 1, Excludes1 1): printed on the block page.

Chapter 2 instructions (Notes 8): printed on the chapter 2 page.

Index entries

  • RAEB (refractory anemia with excess blasts) → D46.2-
  • Myelodysplasia → D46.9
  • Myelodysplastic syndrome → D46.9
  • Preleukemia (syndrome) → D46.9
  • Hemochromatosiswith refractory anemia → D46.1
  • Syndrome5q minus NOS → D46.C
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)refractory → D46.4
  • Myelodysplasiaspecified NEC → D46.Z
  • Myelodysplastic syndromespecified NEC → D46.Z
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)myelodysplastic → D46.9
  • Syndromemyelodysplastic → D46.9
  • Syndromepreleukemic → D46.9
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)refractorywithout ring sideroblasts, so stated → D46.0
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)refractorywithout sideroblasts without excess of blasts → D46.0
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)refractorysideroblastic → D46.1
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)sideroblasticrefractory → D46.1
  • Syndromemyelodysplasticlesions, low grade → D46.20
  • Cytopeniarefractorywith multilineage dysplasia → D46.A
  • Myelodysplastic syndromewith5q deletion → D46.C
  • Myelodysplastic syndromewithisolated del (5q) chromosomal abnormality → D46.C
  • Syndromemyelodysplasticspecified NEC → D46.Z
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)refractorywithhemochromatosis → D46.1
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)refractorywithsideroblasts (ring) (RARS) → D46.1
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)refractorywithexcess of blasts → D46.20
  • Syndromemyelodysplasticwithmultilineage dysplasia → D46.A
  • Cytopeniarefractorywith multilineage dysplasiaand ring sideroblasts (RCMD RS) → D46.B
  • Syndromemyelodysplasticwith5q deletion → D46.C
  • Syndromemyelodysplasticwithisolated del (5q) chromosomal abnormality → D46.C
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)refractorywithexcess of blasts1 (RAEB 1) → D46.21
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)refractorywithexcess of blasts2 (RAEB 2) → D46.22
  • Syndromemyelodysplasticwithmultilineage dysplasiawith ringed sideroblasts → D46.B

NCHS Alphabetic Index. Index first, then the Tabular List.

Hierarchy