DxCodebookFY2027 · Oct 1, 2026 – Sep 30, 2027

E52 diagnosis code · Billable category · FY2027

E52 Niacin deficiency [pellagra]

  • Billable
  • Not CC/MCC
  • POA reported

E52 ICD-10 code: a billable diagnosis code in FY2027; the category has no subdivisions.

Where it sits

  1. Chapter 4 Endocrine, nutritional and metabolic diseases (E00-E89)
  2. E50-E64 Other nutritional deficiencies (E50-E64)
  3. E52 Niacin deficiency [pellagra]
CC / MCC
Neither
MS-DRG
640-641
HCC V28
–
POA
Reported
Code Editor
–
Index entries
28

Instructions

At E52

Inclusion terms

  • Niacin (-tryptophan) deficiency
  • Nicotinamide deficiency
  • Pellagra (alcoholic)

Excludes1

  • sequelae of niacin deficiency (E64.8) E64.8

Notes that also apply

Block E50-E64 instructions (Excludes2 1): printed on the block page.

Chapter 4 instructions (Notes 1, Excludes1 1): printed on the chapter 4 page.

Index entries

  • Niacin (amide) deficiency → E52
  • Nicotinic acid deficiency → E52
  • Pellagra (alcoholic) → E52
  • Alcohol, alcoholic, alcohol-inducedpellagra → E52
  • Avitaminosis (multiple)nicotinic acid → E52
  • Cheilosis (angular)with pellagra → E52
  • Deficiency, deficientniacin (amide) (-tryptophan) → E52
  • Deficiency, deficientnicotinamide → E52
  • Deficiency, deficientnicotinic acid → E52
  • Dermatitis (eczematous)pellagrous → E52
  • Encephalopathy (acute)pellagrous → E52 [G32.89]
  • Erythema, erythematous (infectional) (inflammation)endemic → E52
  • Gingivitispellagrous → E52
  • Glossitis (chronic superficial) (gangrenous) (Moeller's)pellagrous → E52
  • Syndromepellagroid → E52
  • Aciddeficiencyamide nicotinic → E52
  • Aciddeficiencynicotinic → E52
  • Deficiency, deficientvitamin (multiple) NOSnicotinic → E52
  • Deficiency, deficientvitamin (multiple) NOSPP (pellagra-preventing) → E52
  • Dementia (degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety)in (due to)niacin deficiency → E52 [F02.80]
  • Dementia (degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety)in (due to)pellagra → E52 [F02.80]
  • Pellagra (alcoholic)withpolyneuropathy → E52 [G63]
  • Polioencephalopathy, superior hemorrhagicwithpellagra → E52
  • Polyneuropathy (peripheral)in (due to)pellagra → E52 [G63]
  • Avitaminosis (multiple)Bwithpellagra → E52
  • Dementia (degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety)in (due to)niacin deficiencywith behavioral disturbance → E52 [F02.81-]
  • Dementia (degenerative (primary)) (persisting) (unspecified severity) (without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety)in (due to)pellagrawith behavioral disturbance → E52 [F02.81-]
  • Deficiency, deficientvitamin (multiple) NOSB (complex) NOSwithpellagra → E52

NCHS Alphabetic Index. Index first, then the Tabular List.

Medicare grouping and edits

CMS files for E52
CC / MCCNeither
Appendix BMDC 10 Endocrine, Nutritional and Metabolic Diseases and Disorders, MS-DRG 640-641 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes with MCC…)
Code Editor–
POAReported
HCC V28–

CMS: MS-DRG v44 (Appendix B, C), MCE v44, POA list FY2027, 2027 Initial ICD-10-CM Mappings. What the rows mean.

Hierarchy