DxCodebookFY2027 · Oct 1, 2026 – Sep 30, 2027

Category · FY2027

R53 Malaise and fatigue

  • Header · not billable

R53 is not billable. The category heads 6 billable codes in FY2027, grouped under 4 subdivisions.

ICD-10 code by name

What is the ICD-10 code for fatigue?
Fatigue ICD-10 code: R53.83 Other fatigue. Alphabetic Index: Fatigue → R53.83. Search ICD-10 for fatigue

Where it sits

  1. Chapter 18 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
  2. R50-R69 General symptoms and signs (R50-R69)
  3. R53 Malaise and fatigue
Billable codes
6
Subdivisions
4
CC / MCC codes
0 / 1
HCC V28 codes
1
New FY2027
0
Index entries
10

Codes in R53

  1. R53.0
    Neoplastic (malignant) related fatigue
    Billable
    Code first 1

    Code first

    • associated neoplasm
  2. R53.1
    Weakness
    Billable
    Inclusion terms 1, Excludes1 4

    Inclusion terms

    • Asthenia NOS

    Excludes1

    • age-related weakness (R54) R54
    • muscle weakness (generalized) (M62.81) M62.81
    • sarcopenia (M62.84) M62.84
    • senile asthenia (R54) R54
  3. R53.2
    Functional quadriplegia
    BillableMCC180
    Inclusion terms 1, Excludes1 5

    Inclusion terms

    • Complete immobility due to severe physical disability or frailty

    Excludes1

    • frailty NOS (R54) R54
    • hysterical paralysis (F44.4) F44.4
    • immobility syndrome (M62.3) M62.3
    • neurologic quadriplegia (G82.5-) G82.5
    • quadriplegia (G82.50) G82.50
  4. R53.8
    Other malaise and fatigue
    Header
    Excludes1 8

    Excludes1

    • combat exhaustion and fatigue (F43.0) F43.0
    • congenital debility (P96.9) P96.9
    • exhaustion and fatigue due to excessive exertion (T73.3) T73.3
    • exhaustion and fatigue due to exposure (T73.2) T73.2
    • exhaustion and fatigue due to heat (T67.-) T67
    • exhaustion and fatigue due to pregnancy (O26.8-) O26.8
    • exhaustion and fatigue due to recurrent depressive episode (F33-) F33
    • exhaustion and fatigue due to senile debility (R54) R54
  5. R53.81
    Other malaise
    Billable
    Inclusion terms 5, Excludes1 1

    Inclusion terms

    • Chronic debility
    • Debility NOS
    • General physical deterioration
    • Malaise NOS
    • Nervous debility

    Excludes1

    • age-related physical debility (R54) R54
  6. R53.82
    Chronic fatigue, unspecified
    Billable
    Excludes1 4

    Excludes1

    • chronic fatigue syndrome (G93.32) G93.32
    • myalgic encephalomyelitis (G93.32) G93.32
    • other post infection and related fatigue syndromes (G93.39) G93.39
    • postviral fatigue syndrome (G93.31) G93.31
  7. R53.83
    Other fatigue 1 billable code
    Billable

CC/MCC: as a secondary diagnosis, unless the principal diagnosis is on the code’s PDX exclusion list (MS-DRG v44 Appendix C; list on the code card).

Sources of each column.

Instructions

Notes that also apply

Chapter 18 instructions (Notes 9, Excludes2 4): printed on the chapter 18 page.

Index entries

  • Asthenia, asthenic → R53.1
  • Weak, weakening, weakness (generalized) → R53.1
  • Debility (chronic) (general) (nervous) → R53.81
  • Malaise → R53.81
  • Fatigueneoplasm-related → R53.0
  • Immobile, immobilitycomplete, due to severe physical disability or frailty → R53.2
  • Quadriplegiafunctional → R53.2
  • Debility (chronic) (general) (nervous)nervous → R53.81
  • Deteriorationgeneral physical → R53.81
  • Fatiguechronic → R53.82

NCHS Alphabetic Index. Index first, then the Tabular List.

Hierarchy