DxCodebookFY2027 · Oct 1, 2026 – Sep 30, 2027

Category · FY2027

T65 Toxic effect of other and unspecified substances

  • Header · not billable
  • Codes take a 7th character

T65 is not billable. The category heads 192 billable codes in FY2027, grouped under 9 subdivisions. Its codes take a 7th character, so none is complete with fewer than 7 characters.

FY2027 changes under T65: 12 billable codes added. All FY2027 changes.

Index → code

Where it sits

  1. Chapter 19 Injury, poisoning and certain other consequences of external causes (S00-T88)
  2. T51-T65 Toxic effects of substances chiefly nonmedicinal as to source (T51-T65)
  3. T65 Toxic effect of other and unspecified substances
Billable codes
192
Subdivisions
9
CC / MCC codes
0 / 0
HCC V28 codes
15
New FY2027
12
Index entries
7

Codes in T65

  1. T65.0
    Toxic effect of cyanides
    Header
    Excludes1 1

    Excludes1

    • hydrogen cyanide (T57.3-) T57.3
  2. T65.0X
    Toxic effect of cyanides
    Header
  3. T65.0X1
    Toxic effect of cyanides, accidental (unintentional) +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
    Inclusion terms 1

    Inclusion terms

    • Toxic effect of cyanides NOS
  4. T65.0X2
    Toxic effect of cyanides, intentional self-harm +7th: A D S
    Needs 7th character155 (some 7th characters)Exempt: 2 of 3 7th characters
  5. T65.0X3
    Toxic effect of cyanides, assault +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  6. T65.0X4
    Toxic effect of cyanides, undetermined +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  7. T65.1
    Toxic effect of strychnine and its salts
    Header
  8. T65.1X
    Toxic effect of strychnine and its salts
    Header
  9. T65.1X1
    Toxic effect of strychnine and its salts, accidental (unintentional) +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
    Inclusion terms 1

    Inclusion terms

    • Toxic effect of strychnine and its salts NOS
  10. T65.1X2
    Toxic effect of strychnine and its salts, intentional self-harm +7th: A D S
    Needs 7th character155 (some 7th characters)Exempt: 2 of 3 7th characters
  11. T65.1X3
    Toxic effect of strychnine and its salts, assault +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  12. T65.1X4
    Toxic effect of strychnine and its salts, undetermined +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  13. T65.2
    Toxic effect of tobacco and nicotine
    Header
    Excludes2 1

    Excludes2

    • nicotine dependence (F17.-) F17
  14. T65.21
    Toxic effect of chewing tobacco
    Header
  15. T65.211
    Toxic effect of chewing tobacco, accidental (unintentional) +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
    Inclusion terms 1

    Inclusion terms

    • Toxic effect of chewing tobacco NOS
  16. T65.212
    Toxic effect of chewing tobacco, intentional self-harm +7th: A D S
    Needs 7th character155 (some 7th characters)Exempt: 2 of 3 7th characters
  17. T65.213
    Toxic effect of chewing tobacco, assault +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  18. T65.214
    Toxic effect of chewing tobacco, undetermined +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  19. T65.22
    Toxic effect of tobacco cigarettes
    Header
    Inclusion terms 1, Use additional code 1

    Inclusion terms

    • Toxic effect of tobacco smoke

    Use additional code

    • code for exposure to second hand tobacco smoke (Z57.31, Z77.22) Z57.31 Z77.22
  20. T65.221
    Toxic effect of tobacco cigarettes, accidental (unintentional) +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
    Inclusion terms 1

    Inclusion terms

    • Toxic effect of tobacco cigarettes NOS
  21. T65.222
    Toxic effect of tobacco cigarettes, intentional self-harm +7th: A D S
    Needs 7th character155 (some 7th characters)Exempt: 2 of 3 7th characters
  22. T65.223
    Toxic effect of tobacco cigarettes, assault +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  23. T65.224
    Toxic effect of tobacco cigarettes, undetermined +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  24. T65.29
    Toxic effect of other tobacco and nicotine
    Header
  25. T65.291
    Toxic effect of other tobacco and nicotine, accidental (unintentional) +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
    Inclusion terms 1

    Inclusion terms

    • Toxic effect of other tobacco and nicotine NOS
  26. T65.292
    Toxic effect of other tobacco and nicotine, intentional self-harm +7th: A D S
    Needs 7th character155 (some 7th characters)Exempt: 2 of 3 7th characters
  27. T65.293
    Toxic effect of other tobacco and nicotine, assault +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  28. T65.294
    Toxic effect of other tobacco and nicotine, undetermined +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  29. T65.3
    Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues
    Header
    Inclusion terms 3

    Inclusion terms

    • Toxic effect of aniline [benzenamine]
    • Toxic effect of nitrobenzene
    • Toxic effect of trinitrotoluene
  30. T65.3X
    Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues
    Header
  31. T65.3X1
    Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, accidental (unintentional) +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
    Inclusion terms 1

    Inclusion terms

    • Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues NOS
  32. T65.3X2
    Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, intentional self-harm +7th: A D S
    Needs 7th character155 (some 7th characters)Exempt: 2 of 3 7th characters
  33. T65.3X3
    Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, assault +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  34. T65.3X4
    Toxic effect of nitroderivatives and aminoderivatives of benzene and its homologues, undetermined +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  35. T65.4
    Toxic effect of carbon disulfide
    Header
  36. T65.4X
    Toxic effect of carbon disulfide
    Header
  37. T65.4X1
    Toxic effect of carbon disulfide, accidental (unintentional) +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
    Inclusion terms 1

    Inclusion terms

    • Toxic effect of carbon disulfide NOS
  38. T65.4X2
    Toxic effect of carbon disulfide, intentional self-harm +7th: A D S
    Needs 7th character155 (some 7th characters)Exempt: 2 of 3 7th characters
  39. T65.4X3
    Toxic effect of carbon disulfide, assault +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  40. T65.4X4
    Toxic effect of carbon disulfide, undetermined +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  41. T65.5
    Toxic effect of nitroglycerin and other nitric acids and esters
    Header
    Inclusion terms 1

    Inclusion terms

    • Toxic effect of 1,2,3-Propanetriol trinitrate
  42. T65.5X
    Toxic effect of nitroglycerin and other nitric acids and esters
    Header
  43. T65.5X1
    Toxic effect of nitroglycerin and other nitric acids and esters, accidental (unintentional) +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
    Inclusion terms 1

    Inclusion terms

    • Toxic effect of nitroglycerin and other nitric acids and esters NOS
  44. T65.5X2
    Toxic effect of nitroglycerin and other nitric acids and esters, intentional self-harm +7th: A D S
    Needs 7th character155 (some 7th characters)Exempt: 2 of 3 7th characters
  45. T65.5X3
    Toxic effect of nitroglycerin and other nitric acids and esters, assault +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  46. T65.5X4
    Toxic effect of nitroglycerin and other nitric acids and esters, undetermined +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  47. T65.6
    Toxic effect of paints and dyes, not elsewhere classified
    Header
  48. T65.6X
    Toxic effect of paints and dyes, not elsewhere classified
    Header
  49. T65.6X1
    Toxic effect of paints and dyes, not elsewhere classified, accidental (unintentional) +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
    Inclusion terms 1

    Inclusion terms

    • Toxic effect of paints and dyes NOS
  50. T65.6X2
    Toxic effect of paints and dyes, not elsewhere classified, intentional self-harm +7th: A D S
    Needs 7th character155 (some 7th characters)Exempt: 2 of 3 7th characters
  51. T65.6X3
    Toxic effect of paints and dyes, not elsewhere classified, assault +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  52. T65.6X4
    Toxic effect of paints and dyes, not elsewhere classified, undetermined +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  53. T65.8
    Toxic effect of other specified substances
    Header
  54. T65.81
    Toxic effect of latex
    Header
  55. T65.811
    Toxic effect of latex, accidental (unintentional) +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
    Inclusion terms 1

    Inclusion terms

    • Toxic effect of latex NOS
  56. T65.812
    Toxic effect of latex, intentional self-harm +7th: A D S
    Needs 7th character155 (some 7th characters)Exempt: 2 of 3 7th characters
  57. T65.813
    Toxic effect of latex, assault +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  58. T65.814
    Toxic effect of latex, undetermined +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  59. T65.82
    Toxic effect of harmful algae and algae toxins
    Header
    Inclusion terms 7

    Inclusion terms

    • Toxic effect of (harmful) algae bloom NOS
    • Toxic effect of blue-green algae bloom
    • Toxic effect of brown tide
    • Toxic effect of cyanobacteria bloom
    • Toxic effect of Florida red tide
    • Toxic effect of pfiesteria piscicida
    • Toxic effect of red tide
  60. T65.821
    Toxic effect of harmful algae and algae toxins, accidental (unintentional) +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
    Inclusion terms 1

    Inclusion terms

    • Toxic effect of harmful algae and algae toxins NOS
  61. T65.822
    Toxic effect of harmful algae and algae toxins, intentional self-harm +7th: A D S
    Needs 7th character155 (some 7th characters)Exempt: 2 of 3 7th characters
  62. T65.823
    Toxic effect of harmful algae and algae toxins, assault +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  63. T65.824
    Toxic effect of harmful algae and algae toxins, undetermined +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  64. T65.83
    Toxic effect of fiberglass
    Header
  65. T65.831
    Toxic effect of fiberglass, accidental (unintentional) +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
    Inclusion terms 1

    Inclusion terms

    • Toxic effect of fiberglass NOS
  66. T65.832
    Toxic effect of fiberglass, intentional self-harm +7th: A D S
    Needs 7th character155 (some 7th characters)Exempt: 2 of 3 7th characters
  67. T65.833
    Toxic effect of fiberglass, assault +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  68. T65.834
    Toxic effect of fiberglass, undetermined +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  69. T65.84
    Toxic effect of xylazine
    Header
    Use additional code 5

    Use additional code

    • code(s) for all associated manifestations, such as:
    • cellulitis and acute lymphangitis (L03.-) L03
    • cutaneous abscess, furuncle and carbuncle (L02.-) L02
    • non-pressure chronic ulcer of lower limb, not elsewhere classified (L97.-) L97
    • non-pressure chronic ulcer of skin, not elsewhere classified (L98.4-) L98.4
  70. T65.841
    Toxic effect of xylazine, accidental (unintentional) +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
    Inclusion terms 1

    Inclusion terms

    • Toxic effect of xylazine NOS
  71. T65.842
    Toxic effect of xylazine, intentional self-harm +7th: A D S
    Needs 7th character155 (some 7th characters)Exempt: 2 of 3 7th characters
  72. T65.843
    Toxic effect of xylazine, assault +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  73. T65.844
    Toxic effect of xylazine, undetermined +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  74. T65.85
    Toxic effect of medetomidine New FY2027
    Header
    Use additional code 3

    Use additional code

    • code to identify associated manifestations, such as:
    • bradycardia NOS (R00.1) R00.1
    • somnolence, stupor and coma (R40.-) R40
  75. T65.851
    Toxic effect of medetomidine, accidental (unintentional) New FY2027 +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
    Inclusion terms 1

    Inclusion terms

    • Toxic effect of medetomidine NOS
  76. T65.852
    Toxic effect of medetomidine, intentional self-harm New FY2027 +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  77. T65.853
    Toxic effect of medetomidine, assault New FY2027 +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  78. T65.854
    Toxic effect of medetomidine, undetermined New FY2027 +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  79. T65.89
    Toxic effect of other specified substances
    Header
  80. T65.891
    Toxic effect of other specified substances, accidental (unintentional) +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
    Inclusion terms 1

    Inclusion terms

    • Toxic effect of other specified substances NOS
  81. T65.892
    Toxic effect of other specified substances, intentional self-harm +7th: A D S
    Needs 7th character155 (some 7th characters)Exempt: 2 of 3 7th characters
  82. T65.893
    Toxic effect of other specified substances, assault +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  83. T65.894
    Toxic effect of other specified substances, undetermined +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  84. T65.9
    Toxic effect of unspecified substance
    Header
  85. T65.91
    Toxic effect of unspecified substance, accidental (unintentional) +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
    Inclusion terms 1

    Inclusion terms

    • Poisoning NOS
  86. T65.92
    Toxic effect of unspecified substance, intentional self-harm +7th: A D S
    Needs 7th character155 (some 7th characters)Exempt: 2 of 3 7th characters
  87. T65.93
    Toxic effect of unspecified substance, assault +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters
  88. T65.94
    Toxic effect of unspecified substance, undetermined +7th: A D S
    Needs 7th characterExempt: 2 of 3 7th characters

Sources of each column. Rows marked +7th need a 7th character: pick one to build the full code; its code card has its own flags.

Instructions

Notes that also apply

Block T51-T65 instructions (Notes 1, Excludes1 1, Use additional code 4): printed on the block page.

Chapter 19 instructions (Notes 2, Excludes2 2, Use additional code 1): printed on the chapter 19 page.

7th characters

7th characters for T65 defined here

The appropriate 7th character is to be added to each code from category T65

7th characters for T65
7thMeaning (NCHS)
Ainitial encounter
Dsubsequent encounter
Ssequela

A code that takes a 7th character is invalid without it; the placeholder X fills a code shorter than 6 characters (Official Guidelines I.A.5). How 7th characters work.

Index entries

  • Red tide → T65.82-
  • Toxic (poisoning) → T65.91
  • Poisoning (acute)nicotine (tobacco) → T65.2-
  • Poisoning (acute)tobacco (nicotine) → T65.2-
  • Poisoning (acute)latex → T65.81-
  • Poisoning (acute)algae and toxins → T65.82-
  • Poisoning (acute)specified substance NEC → T65.891

NCHS Alphabetic Index. Index first, then the Tabular List.

Hierarchy