DxCodebookFY2027 · Oct 1, 2026 – Sep 30, 2027

Category · FY2027

D68 Other coagulation defects

  • Header · not billable

D68 is not billable. The category heads 25 billable codes in FY2027, grouped under 9 subdivisions.

Index → code

Where it sits

  1. Chapter 3 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
  2. D65-D69 Coagulation defects, purpura and other hemorrhagic conditions (D65-D69)
  3. D68 Other coagulation defects
Billable codes
25
Subdivisions
9
CC / MCC codes
25 / 0
HCC V28 codes
13
New FY2027
0
Index entries
187

Codes in D68

  1. D68.0
    Von Willebrand disease
    Header
    Excludes1 3

    Excludes1

    • capillary fragility (hereditary) (D69.8) D69.8
    • factor VIII deficiency NOS (D66) D66
    • factor VIII deficiency with functional defect (D66) D66
  2. D68.00
    Von Willebrand disease, unspecified
    BillableCC112
  3. D68.01
    Von Willebrand disease, type 1
    BillableCC112
    Inclusion terms 2

    Inclusion terms

    • Partial quantitative deficiency of von Willebrand factor
    • Type 1C von Willebrand disease
  4. D68.02
    Von Willebrand disease, type 2
    Header
    Inclusion terms 1

    Inclusion terms

    • Qualitative defects of von Willebrand factor
  5. D68.020
    Von Willebrand disease, type 2A
    BillableCC112
    Inclusion terms 1

    Inclusion terms

    • Qualitative defects of von Willebrand factor with decreased platelet adhesion and selective deficiency of high-molecular-weight multimers
  6. D68.021
    Von Willebrand disease, type 2B
    BillableCC112
    Inclusion terms 3

    Inclusion terms

    • Qualitative defects of von Willebrand factor with high-molecular-weight von Willebrand factor loss
    • Qualitative defects of von Willebrand factor with hyper-adhesive forms
    • Qualitative defects of von Willebrand factor with increased affinity for platelet glycoprotein lb
  7. D68.022
    Von Willebrand disease, type 2M
    BillableCC112
    Inclusion terms 1

    Inclusion terms

    • Qualitative defects of von Willebrand factor with defective platelet adhesion with a normal size distribution of von Willebrand factor multimers
  8. D68.023
    Von Willebrand disease, type 2N
    BillableCC112
    Inclusion terms 2

    Inclusion terms

    • Qualitative defects of von Willebrand factor with defective von Willebrand factor to factor VIII binding
    • Qualitative defects of von Willebrand factor with markedly decreased affinity for factor VIII
  9. D68.029
    Von Willebrand disease, type 2, unspecified
    BillableCC112
    Inclusion terms 1

    Inclusion terms

    • Qualitative defect in von Willebrand factor function, with no further subtyping
  10. D68.03
    Von Willebrand disease, type 3
    BillableCC112
    Inclusion terms 2

    Inclusion terms

    • (Near) complete absence of von Willebrand factor
    • Total quantitative deficiency of von Willebrand factor
  11. D68.04
    Acquired von Willebrand disease
    BillableCC112
    Inclusion terms 1

    Inclusion terms

    • Acquired von Willebrand syndrome
  12. D68.09
    Other von Willebrand disease
    BillableCC112
    Inclusion terms 2, Code also 1

    Inclusion terms

    • Platelet-type von Willebrand disease
    • Pseudo-von Willebrand disease

    Code also

    • , if applicable, qualitative platelet defects (D69.1-) D69.1
  13. D68.1
    Hereditary factor XI deficiency
    BillableCC112
    Inclusion terms 3

    Inclusion terms

    • Hemophilia C
    • Plasma thromboplastin antecedent [PTA] deficiency
    • Rosenthal's disease
  14. D68.2
    Hereditary deficiency of other clotting factors
    BillableCC112
    Inclusion terms 13

    Inclusion terms

    • AC globulin deficiency
    • Congenital afibrinogenemia
    • Deficiency of factor I [fibrinogen]
    • Deficiency of factor II [prothrombin]
    • Deficiency of factor V [labile]
    • Deficiency of factor VII [stable]
    • Deficiency of factor X [Stuart-Prower]
    • Deficiency of factor XII [Hageman]
    • Deficiency of factor XIII [fibrin stabilizing]
    • Dysfibrinogenemia (congenital)
    • Hypoproconvertinemia
    • Owren's disease
    • Proaccelerin deficiency
  15. D68.3
    Hemorrhagic disorder due to circulating anticoagulants
    Header
  16. D68.31
    Hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors
    Header
  17. D68.311
    Acquired hemophilia
    BillableCC112
    Inclusion terms 3

    Inclusion terms

    • Autoimmune hemophilia
    • Autoimmune inhibitors to clotting factors
    • Secondary hemophilia
  18. D68.312
    Antiphospholipid antibody with hemorrhagic disorder
    BillableCC
    Inclusion terms 2, Excludes1 3, Excludes2 4

    Inclusion terms

    • Lupus anticoagulant (LAC) with hemorrhagic disorder
    • Systemic lupus erythematosus [SLE] inhibitor with hemorrhagic disorder

    Excludes1

    • antiphospholipid antibody, finding without diagnosis (R76.0) R76.0
    • lupus anticoagulant (LAC) finding without diagnosis (R76.0) R76.0
    • systemic lupus erythematosus [SLE] inhibitor finding without diagnosis (R76.0) R76.0

    Excludes2

    • antiphospholipid antibody syndrome (D68.61) D68.61
    • antiphospholipid antibody with hypercoagulable state (D68.61) D68.61
    • lupus anticoagulant (LAC) with hypercoagulable state (D68.62) D68.62
    • systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state (D68.62) D68.62
  19. D68.318
    Other hemorrhagic disorder due to intrinsic circulating anticoagulants, antibodies, or inhibitors
    BillableCC
    Inclusion terms 6

    Inclusion terms

    • Antithromboplastinemia
    • Antithromboplastinogenemia
    • Hemorrhagic disorder due to intrinsic increase in antithrombin
    • Hemorrhagic disorder due to intrinsic increase in anti-VIIIa
    • Hemorrhagic disorder due to intrinsic increase in anti-IXa
    • Hemorrhagic disorder due to intrinsic increase in anti-XIa
  20. D68.32
    Hemorrhagic disorder due to extrinsic circulating anticoagulants
    BillableCC
    Inclusion terms 4, Use additional code 1

    Inclusion terms

    • Drug-induced hemorrhagic disorder
    • Hemorrhagic disorder due to increase in anti-IIa
    • Hemorrhagic disorder due to increase in anti-Xa
    • Hyperheparinemia

    Use additional code

    • code for adverse effect, if applicable, to identify drug (T45.515, T45.525) T45.515 T45.525
  21. D68.4
    Acquired coagulation factor deficiency
    BillableCC
    Inclusion terms 2, Excludes1 1

    Inclusion terms

    • Deficiency of coagulation factor due to liver disease
    • Deficiency of coagulation factor due to vitamin K deficiency

    Excludes1

    • vitamin K deficiency of newborn (P53) P53
  22. D68.5
    Primary thrombophilia
    Header
    Inclusion terms 1, Excludes1 9

    Inclusion terms

    • Primary hypercoagulable states

    Excludes1

    • antiphospholipid syndrome (D68.61) D68.61
    • lupus anticoagulant (D68.62) D68.62
    • secondary activated protein C resistance (D68.69) D68.69
    • secondary antiphospholipid antibody syndrome (D68.69) D68.69
    • secondary lupus anticoagulant with hypercoagulable state (D68.69) D68.69
    • secondary systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state (D68.69) D68.69
    • systemic lupus erythematosus [SLE] inhibitor finding without diagnosis (R76.0) R76.0
    • systemic lupus erythematosus [SLE] inhibitor with hemorrhagic disorder (D68.312) D68.312
    • thrombotic thrombocytopenic purpura (M31.19) M31.19
  23. D68.51
    Activated protein C resistance
    BillableCC
    Inclusion terms 1

    Inclusion terms

    • Factor V Leiden mutation
  24. D68.52
    Prothrombin gene mutation
    BillableCC
  25. D68.59
    Other primary thrombophilia
    BillableCC
    Inclusion terms 7

    Inclusion terms

    • Antithrombin III deficiency
    • Hypercoagulable state NOS
    • Primary hypercoagulable state NEC
    • Primary thrombophilia NEC
    • Protein C deficiency
    • Protein S deficiency
    • Thrombophilia NOS
  26. D68.6
    Other thrombophilia
    Header
    Inclusion terms 1, Excludes1 3

    Inclusion terms

    • Other hypercoagulable states

    Excludes1

    • diffuse or disseminated intravascular coagulation [DIC] (D65) D65
    • heparin induced thrombocytopenia (HIT) (D75.82-) D75.82
    • hyperhomocysteinemia (E72.11) E72.11
  27. D68.61
    Antiphospholipid syndrome
    BillableCC
    Inclusion terms 2, Excludes1 1, Excludes2 2

    Inclusion terms

    • Anticardiolipin syndrome
    • Antiphospholipid antibody syndrome

    Excludes1

    • anti-phospholipid antibody, finding without diagnosis (R76.0) R76.0

    Excludes2

    • anti-phospholipid antibody with hemorrhagic disorder (D68.312) D68.312
    • lupus anticoagulant syndrome (D68.62) D68.62
  28. D68.62
    Lupus anticoagulant syndrome
    BillableCC
    Inclusion terms 2, Excludes1 1, Excludes2 3

    Inclusion terms

    • Lupus anticoagulant
    • Presence of systemic lupus erythematosus [SLE] inhibitor

    Excludes1

    • lupus anticoagulant (LAC) finding without diagnosis (R76.0) R76.0

    Excludes2

    • anticardiolipin syndrome (D68.61) D68.61
    • antiphospholipid syndrome (D68.61) D68.61
    • lupus anticoagulant (LAC) with hemorrhagic disorder (D68.312) D68.312
  29. D68.69
    Other thrombophilia
    BillableCC
    Inclusion terms 3, Code also 1

    Inclusion terms

    • COVID-19 associated hypercoagulability
    • Hypercoagulable states NEC
    • Secondary hypercoagulable state NOS

    Code also

    • , if applicable, associated condition
  30. D68.8
    Other specified coagulation defects
    BillableCC
    Inclusion terms 1, Excludes1 1, Code also 1

    Inclusion terms

    • COVID-19 associated coagulopathy

    Excludes1

    • hemorrhagic disease of newborn (P53) P53

    Code also

    • , if applicable, associated condition
  31. D68.9
    Coagulation defect, unspecified
    BillableCC

CC/MCC: as a secondary diagnosis, unless the principal diagnosis is on the code’s PDX exclusion list (MS-DRG v44 Appendix C; list on the code card).

Sources of each column.

Instructions

At D68

Excludes1

  • abnormal coagulation profile NOS (R79.1) R79.1

Excludes2

  • coagulation defects complicating abortion or ectopic or molar pregnancy (O00-O07, O08.1) O00 O07 O08.1
  • coagulation defects complicating pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72.3) O45.0 O46.0 O67.0 O72.3

Notes that also apply

Chapter 3 instructions (Excludes2 9): printed on the chapter 3 page.

Index entries

  • Rosenthal's disease or syndrome → D68.1
  • Dysfibrinogenemia (congenital) → D68.2
  • Fibrinopenia (hereditary) → D68.2
  • Hageman's factor defect, deficiency or disease → D68.2
  • Hypoproconvertinemia, congenital (hereditary) → D68.2
  • Hypoprothrombinemia (congenital) (hereditary) (idiopathic) → D68.2
  • Owren's disease or syndrome (parahemophilia) → D68.2
  • Parahemophilia → D68.2
  • Stuart deficiency disease (factor X) → D68.2
  • Stuart-Prower factor deficiency (factor X) → D68.2
  • Anticoagulant, circulating (intrinsic) → D68.318
  • Antithromboplastinemia → D68.318
  • Antithromboplastinogenemia → D68.318
  • Circulating anticoagulants → D68.318
  • Hyperheparinemia → D68.32
  • Hyperprothrombinemia, causing coagulation factor deficiency → D68.4
  • Activated protein C resistance → D68.51
  • Prothrombin gene mutation → D68.52
  • Hypercoagulable (state) → D68.59
  • Hypercoagulation (state) → D68.59
  • Thrombophilia → D68.59
  • Anticardiolipin syndrome → D68.61
  • Inhibitor, systemic lupus erythematosus (presence of) → D68.62
  • Afibrinogenemia → D68.8
  • Fibrinogenopenia → D68.8
  • Hypofibrinogenemia → D68.8
  • Disease, diseasedvon Willebrand (-Jürgens) (angiohemophilia) → D68.00
  • Absence (of) (organ or part) (complete or partial)von Willebrand factor, complete (near) → D68.03
  • Deficiency, deficientPTA (plasma thromboplastin antecedent) → D68.1
  • Disease, diseasedRosenthal's (factor XI deficiency) → D68.1
  • Hemophilia (classical) (familial) (hereditary)C → D68.1
  • Absence (of) (organ or part) (complete or partial)fibrinogen (congenital) → D68.2
  • Afibrinogenemiacongenital → D68.2
  • Defect, defectivefibrin polymerization → D68.2
  • Defect, defectiveHageman (factor) → D68.2
  • Deficiency, deficientaccelerator globulin (Ac G) (blood) → D68.2
  • Deficiency, deficientAC globulin (congenital) (hereditary) → D68.2
  • Deficiency, deficientactivating factor (blood) → D68.2
  • Deficiency, deficientclotting factor NEC (hereditary) → D68.2
  • Deficiency, deficientcontact factor → D68.2

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