Category · FY2027
T80 Complications following infusion, transfusion and therapeutic injection
- Header · not billable
- Codes take a 7th character
T80 is not billable. The category heads 114 billable codes in FY2027, grouped under 10 subdivisions. Its codes take a 7th character, so none is complete with fewer than 7 characters.
Index → code
Where it sits
- Chapter 19 Injury, poisoning and certain other consequences of external causes (S00-T88)
- T80-T88 Complications of surgical and medical care, not elsewhere classified (T80-T88)
- T80 Complications following infusion, transfusion and therapeutic injection
- Billable codes
- 114
- Subdivisions
- 10
- CC / MCC codes
- 33 / 1
- HCC V28 codes
- 0
- New FY2027
- 0
- Index entries
- 146
Codes in T80
- T80.0Air embolism following infusion, transfusion and therapeutic injection +7th: A D SNeeds 7th characterMCC AExempt: 2 of 3 7th characters
- T80.1Vascular complications following infusion, transfusion and therapeutic injection +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Excludes2 4, Use additional code 1
Excludes2
Use additional code
- code to identify the vascular complication
- T80.2Infections following infusion, transfusion and therapeutic injectionHeader
Excludes2 2, Use additional code 3
Excludes2
- T80.21Infection due to central venous catheterHeader
Inclusion terms 1
Inclusion terms
- Infection due to pulmonary artery catheter (Swan-Ganz catheter)
- T80.211Bloodstream infection due to central venous catheter +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 8
Inclusion terms
- Catheter-related bloodstream infection (CRBSI) NOS
- Central line-associated bloodstream infection (CLABSI)
- Bloodstream infection due to Hickman catheter
- Bloodstream infection due to peripherally inserted central catheter (PICC)
- Bloodstream infection due to portacath (port-a-cath)
- Bloodstream infection due to pulmonary artery catheter
- Bloodstream infection due to triple lumen catheter
- Bloodstream infection due to umbilical venous catheter
- T80.212Local infection due to central venous catheter +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 9
Inclusion terms
- Exit or insertion site infection
- Local infection due to Hickman catheter
- Local infection due to peripherally inserted central catheter (PICC)
- Local infection due to portacath (port-a-cath)
- Local infection due to pulmonary artery catheter
- Local infection due to triple lumen catheter
- Local infection due to umbilical venous catheter
- Port or reservoir infection
- Tunnel infection
- T80.218Other infection due to central venous catheter +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 7
Inclusion terms
- Other central line-associated infection
- Other infection due to Hickman catheter
- Other infection due to peripherally inserted central catheter (PICC)
- Other infection due to portacath (port-a-cath)
- Other infection due to pulmonary artery catheter
- Other infection due to triple lumen catheter
- Other infection due to umbilical venous catheter
- T80.219Unspecified infection due to central venous catheter +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 7
Inclusion terms
- Central line-associated infection NOS
- Unspecified infection due to Hickman catheter
- Unspecified infection due to peripherally inserted central catheter (PICC)
- Unspecified infection due to portacath (port-a-cath)
- Unspecified infection due to pulmonary artery catheter
- Unspecified infection due to triple lumen catheter
- Unspecified infection due to umbilical venous catheter
- T80.22Acute infection following transfusion, infusion, or injection of blood and blood products +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
- T80.29Infection following other infusion, transfusion and therapeutic injection +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
- T80.3ABO incompatibility reaction due to transfusion of blood or blood productsHeader
Excludes1 1
Excludes1
- minor blood group antigens reactions (Duffy) (E) (K) (Kell) (Kidd) (Lewis) (M) (N) (P) (S) (T80.A-) T80.A
- T80.30ABO incompatibility reaction due to transfusion of blood or blood products, unspecified +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 2
Inclusion terms
- ABO incompatibility blood transfusion NOS
- Reaction to ABO incompatibility from transfusion NOS
- T80.31ABO incompatibility with hemolytic transfusion reactionHeader
- T80.310ABO incompatibility with acute hemolytic transfusion reaction +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 2
Inclusion terms
- ABO incompatibility with hemolytic transfusion reaction less than 24 hours after transfusion
- Acute hemolytic transfusion reaction (AHTR) due to ABO incompatibility
- T80.311ABO incompatibility with delayed hemolytic transfusion reaction +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 2
Inclusion terms
- ABO incompatibility with hemolytic transfusion reaction 24 hours or more after transfusion
- Delayed hemolytic transfusion reaction (DHTR) due to ABO incompatibility
- T80.319ABO incompatibility with hemolytic transfusion reaction, unspecified +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 2
Inclusion terms
- ABO incompatibility with hemolytic transfusion reaction at unspecified time after transfusion
- Hemolytic transfusion reaction (HTR) due to ABO incompatibility NOS
- T80.39Other ABO incompatibility reaction due to transfusion of blood or blood products +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 3
Inclusion terms
- Delayed serologic transfusion reaction (DSTR) from ABO incompatibility
- Other ABO incompatible blood transfusion
- Other reaction to ABO incompatible blood transfusion
- T80.4Rh incompatibility reaction due to transfusion of blood or blood productsHeader
Inclusion terms 1
Inclusion terms
- Reaction due to incompatibility of Rh antigens (C) (c) (D) (E) (e)
- T80.40Rh incompatibility reaction due to transfusion of blood or blood products, unspecified +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 2
Inclusion terms
- Reaction due to Rh factor in transfusion NOS
- Rh incompatible blood transfusion NOS
- T80.41Rh incompatibility with hemolytic transfusion reactionHeader
- T80.410Rh incompatibility with acute hemolytic transfusion reaction +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 2
Inclusion terms
- Acute hemolytic transfusion reaction (AHTR) due to Rh incompatibility
- Rh incompatibility with hemolytic transfusion reaction less than 24 hours after transfusion
- T80.411Rh incompatibility with delayed hemolytic transfusion reaction +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 2
Inclusion terms
- Delayed hemolytic transfusion reaction (DHTR) due to Rh incompatibility
- Rh incompatibility with hemolytic transfusion reaction 24 hours or more after transfusion
- T80.419Rh incompatibility with hemolytic transfusion reaction, unspecified +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 2
Inclusion terms
- Rh incompatibility with hemolytic transfusion reaction at unspecified time after transfusion
- Hemolytic transfusion reaction (HTR) due to Rh incompatibility NOS
- T80.49Other Rh incompatibility reaction due to transfusion of blood or blood products +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 2
Inclusion terms
- Delayed serologic transfusion reaction (DSTR) from Rh incompatibility
- Other reaction to Rh incompatible blood transfusion
- T80.ANon-ABO incompatibility reaction due to transfusion of blood or blood productsHeader
Inclusion terms 1
Inclusion terms
- Reaction due to incompatibility of minor antigens (Duffy) (Kell) (Kidd) (Lewis) (M) (N) (P) (S)
- T80.A0Non-ABO incompatibility reaction due to transfusion of blood or blood products, unspecified +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 1
Inclusion terms
- Non-ABO antigen incompatibility reaction from transfusion NOS
- T80.A1Non-ABO incompatibility with hemolytic transfusion reactionHeader
- T80.A10Non-ABO incompatibility with acute hemolytic transfusion reaction +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 2
Inclusion terms
- Acute hemolytic transfusion reaction (AHTR) due to non-ABO incompatibility
- Non-ABO incompatibility with hemolytic transfusion reaction less than 24 hours after transfusion
- T80.A11Non-ABO incompatibility with delayed hemolytic transfusion reaction +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 2
Inclusion terms
- Delayed hemolytic transfusion reaction (DHTR) due to non-ABO incompatibility
- Non-ABO incompatibility with hemolytic transfusion reaction 24 or more hours after transfusion
- T80.A19Non-ABO incompatibility with hemolytic transfusion reaction, unspecified +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 2
Inclusion terms
- Hemolytic transfusion reaction (HTR) due to non-ABO incompatibility NOS
- Non-ABO incompatibility with hemolytic transfusion reaction at unspecified time after transfusion
- T80.A9Other non-ABO incompatibility reaction due to transfusion of blood or blood products +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 2
Inclusion terms
- Delayed serologic transfusion reaction (DSTR) from non-ABO incompatibility
- Other reaction to non-ABO incompatible blood transfusion
- T80.5Anaphylactic reaction due to serumHeader
Inclusion terms 4, Excludes1 5
Inclusion terms
- Allergic shock due to serum
- Anaphylactic shock due to serum
- Anaphylactoid reaction due to serum
- Anaphylaxis due to serum
Excludes1
- ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-) T80.3
- allergic reaction or shock NOS (T78.2) T78.2
- anaphylactic reaction or shock NOS (T78.2) T78.2
- anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6) T88.6
- other serum reaction (T80.6-) T80.6
- T80.51Anaphylactic reaction due to administration of blood and blood products +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
- T80.52Anaphylactic reaction due to vaccination +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
- T80.59Anaphylactic reaction due to other serum +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
- T80.6
- T80.61Other serum reaction due to administration of blood and blood products +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
- T80.62Other serum reaction due to vaccination +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
- T80.69Other serum reaction due to other serum +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Code also 1
Code also
- , if applicable, arthropathy in hypersensitivity reactions classified elsewhere (M36.4) M36.4
- T80.8Other complications following infusion, transfusion and therapeutic injectionHeader
- T80.81Extravasation of vesicant agentHeader
Inclusion terms 1
Inclusion terms
- Infiltration of vesicant agent
- T80.810Extravasation of vesicant antineoplastic chemotherapy +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 1
Inclusion terms
- Infiltration of vesicant antineoplastic chemotherapy
- T80.818Extravasation of other vesicant agent +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 1
Inclusion terms
- Infiltration of other vesicant agent
- T80.82Complication of immune effector cellular therapy +7th: A D SNeeds 7th characterExempt: 2 of 3 7th characters
Inclusion terms 2, Excludes2 3, Use additional code 3
Inclusion terms
- Complication of chimeric antigen receptor (CAR-T) cell therapy
- Complication of IEC therapy
Excludes2
- T80.89Other complications following infusion, transfusion and therapeutic injection +7th: A D SNeeds 7th characterExempt: 2 of 3 7th characters
Inclusion terms 1, Use additional code 1
Inclusion terms
- Delayed serologic transfusion reaction (DSTR), unspecified incompatibility
Use additional code
- code to identify graft-versus-host reaction, if applicable, (D89.81-) D89.81
- T80.9Unspecified complication following infusion, transfusion and therapeutic injectionHeader
- T80.90Unspecified complication following infusion and therapeutic injection +7th: A D SNeeds 7th characterExempt: 2 of 3 7th characters
- T80.91Hemolytic transfusion reaction, unspecified incompatibilityHeader
- T80.910Acute hemolytic transfusion reaction, unspecified incompatibility +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
- T80.911Delayed hemolytic transfusion reaction, unspecified incompatibility +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
- T80.919Hemolytic transfusion reaction, unspecified incompatibility, unspecified as acute or delayed +7th: A D SNeeds 7th characterCC AExempt: 2 of 3 7th characters
Inclusion terms 1
Inclusion terms
- Hemolytic transfusion reaction NOS
- T80.92Unspecified transfusion reaction +7th: A D SNeeds 7th characterExempt: 2 of 3 7th characters
Inclusion terms 1
Inclusion terms
- Transfusion reaction NOS
CC/MCC: as a secondary diagnosis, unless the principal diagnosis is on the code’s PDX exclusion list (MS-DRG v44 Appendix C; list on the code card).
Sources of each column. Rows marked +7th need a 7th character: pick one to build the full code; its code card has its own flags.
Instructions
At T80
Includes
- complications following perfusion
Excludes2
- bone marrow transplant rejection (T86.01) T86.01
- febrile nonhemolytic transfusion reaction (R50.84) R50.84
- fluid overload due to transfusion (E87.71) E87.71
- posttransfusion purpura (D69.51) D69.51
- transfusion associated circulatory overload (TACO) (E87.71) E87.71
- transfusion (red blood cell) associated hemochromatosis (E83.111) E83.111
- transfusion related acute lung injury (TRALI) (J95.84) J95.84
Notes that also apply
Block T80-T88 instructions (Excludes2 21, Use additional code 3): printed on the block page.
Chapter 19 instructions (Notes 2, Excludes2 2, Use additional code 1): printed on the chapter 19 page.
7th characters
7th characters for T80 defined here
The appropriate 7th character is to be added to each code from category T80
| 7th | Meaning (NCHS) |
|---|---|
| A | initial encounter |
| D | subsequent encounter |
| S | sequela |
A code that takes a 7th character is invalid without it; the placeholder X fills a code shorter than 6 characters (Official Guidelines I.A.5). How 7th characters work.
Index entries
- Infection, infected, infective (opportunistic)›catheter-related bloodstream (CRBSI) → T80.211
- Infection, infected, infective (opportunistic)›port or reservoir → T80.212
- Infection, infected, infective (opportunistic)›tunnel → T80.212
- Infection, infected, infective (opportunistic)›central line-associated → T80.219
- Allergy, allergic (reaction) (to)›serum → T80.69
- Disease, diseased›serum NEC → T80.69
- Effect, adverse›serum NEC → T80.69
- Intoxication›serum → T80.69
- Neuritis (rheumatoid)›serum → T80.69
- Protein›sickness → T80.69
- Rash (toxic)›serum → T80.69
- Reaction›serum → T80.69
- Serum›allergy, allergic reaction → T80.69
- Serum›arthritis → T80.69
- Serum›complication or reaction NEC → T80.69
- Serum›disease NEC → T80.69
- Serum›intoxication → T80.69
- Serum›neuritis → T80.69
- Serum›poisoning NEC → T80.69
- Serum›rash NEC → T80.69
- Serum›reaction NEC → T80.69
- Serum›sickness NEC → T80.69
- Serum›urticaria → T80.69
- Sickness›protein → T80.69
- Sickness›serum NEC → T80.69
- Urticaria›serum → T80.69
- Complication(s) (from) (of)›chimeric antigen receptor (CAR-T) cell therapy → T80.82
- Complication(s) (from) (of)›IEC (immune effector cellular) therapy → T80.82
- Complication(s) (from) (of)›immune effector cellular (IEC) therapy → T80.82
- Hemoglobinemia›due to blood transfusion → T80.89
- Hemosiderosis (dietary)›transfusion → T80.89
- Complication(s) (from) (of)›extracorporeal circulation → T80.90
- Complication(s) (from) (of)›infusion (procedure) → T80.90
- Complication(s) (from) (of)›injection (procedure) → T80.90
- Complication(s) (from) (of)›perfusion NEC → T80.90
- Complication(s) (from) (of)›transfusion (blood) (lymphocytes) (plasma) → T80.92
- Complication(s) (from) (of)›infusion (procedure)›air embolism → T80.0
- Complication(s) (from) (of)›transfusion (blood) (lymphocytes) (plasma)›air embolism → T80.0
- Complication(s) (from) (of)›vascular›following infusion, therapeutic injection or transfusion → T80.1
- Infection, infected, infective (opportunistic)›central line-associated›bloodstream (CLABSI) → T80.211
106 more, longer entries are not listed; the search box finds them by word.
NCHS Alphabetic Index. Index first, then the Tabular List.