DxCodebookFY2027 · Oct 1, 2026 – Sep 30, 2027

Category · FY2027

Z17 Estrogen, and other hormones and factors receptor status

  • Header · not billable

Z17 is not billable. The category heads 10 billable codes in FY2027, grouped under 5 subdivisions.

Index → code

  • Triplenegative breast cancer (TNBC) → Z17.421
  • Status (post)estrogen receptornegative → Z17.1
  • Status (post)estrogen receptorpositive → Z17.0

Where it sits

  1. Chapter 21 Factors influencing health status and contact with health services (Z00-Z99)
  2. Z17 Estrogen, and other hormones and factors receptor status (Z17)
  3. Z17 Estrogen, and other hormones and factors receptor status
Billable codes
10
Subdivisions
5
CC / MCC codes
0 / 0
HCC V28 codes
0
New FY2027
0
Index entries
11

Codes in Z17

  1. Z17.0
    Estrogen receptor positive status [ER+]
    BillableExempt
  2. Z17.1
    Estrogen receptor negative status [ER-]
    BillableExempt
  3. Z17.2
    Progesterone receptor status
    Header
  4. Z17.21
    Progesterone receptor positive status
    BillableExempt
    Inclusion terms 1

    Inclusion terms

    • PR+
  5. Z17.22
    Progesterone receptor negative status
    BillableExempt
    Inclusion terms 1

    Inclusion terms

    • PR-
  6. Z17.3
    Human epidermal growth factor 2 receptor
    Header
  7. Z17.31
    Human epidermal growth factor receptor 2 positive status
    BillableExempt
    Inclusion terms 1

    Inclusion terms

    • HER2+
  8. Z17.32
    Human epidermal growth factor receptor 2 negative status
    BillableExempt
    Inclusion terms 1

    Inclusion terms

    • HER2-
  9. Z17.4
    Combined receptor status
    Header
    Notes 1

    Notes

    • Assign a code from subcategory Z17.4- when only a combined receptor status is documented Z17.4
  10. Z17.41
    Hormone receptor positive
    Header
    Inclusion terms 1

    Inclusion terms

    • HR+
  11. Z17.410
    Hormone receptor positive with human epidermal growth factor receptor 2 positive status
    BillableExempt
    Inclusion terms 1

    Inclusion terms

    • HR+ with HER2+
  12. Z17.411
    Hormone receptor positive with human epidermal growth factor receptor 2 negative status
    BillableExempt
    Inclusion terms 1

    Inclusion terms

    • HR+ with HER2-
  13. Z17.42
    Hormone receptor negative
    Header
    Inclusion terms 1

    Inclusion terms

    • HR-
  14. Z17.420
    Hormone receptor negative with human epidermal growth factor receptor 2 positive status
    BillableExempt
    Inclusion terms 1

    Inclusion terms

    • HR- with HER2+
  15. Z17.421
    Hormone receptor negative with human epidermal growth factor receptor 2 negative status
    BillableExempt
    Inclusion terms 3

    Inclusion terms

    • HR- with HER2-
    • TNBC
    • Triple negative breast cancer

Sources of each column.

Instructions

At Z17

Notes

Code first

  • malignant neoplasm, such as:
  • malignant neoplasm of breast (C50.-) C50
  • malignant neoplasm of ovary (C56.-) C56

Notes that also apply

Chapter 21 instructions (Notes 3): printed on the chapter 21 page.

Index entries

  • Triplenegative breast cancer (TNBC) → Z17.421
  • Status (post)estrogen receptorpositive → Z17.0
  • Status (post)estrogen receptornegative → Z17.1
  • Status (post)progesterone receptorpositive → Z17.21
  • Status (post)progesterone receptornegative → Z17.22
  • Status (post)human epidermal growth factor 2 receptorpositive → Z17.31
  • Status (post)human epidermal growth factor 2 receptornegative → Z17.32
  • Status (post)combined receptorpositivehormone receptor positive with human epidermal growth factor receptor 2 positive → Z17.410
  • Status (post)combined receptorpositivehormone receptor positive with human epidermal growth factor receptor 2 negative → Z17.411
  • Status (post)combined receptornegativehormone receptor negative with human epidermal growth factor receptor 2 positive → Z17.420
  • Status (post)combined receptornegativehormone receptor negative with human epidermal growth factor receptor 2 negative → Z17.421

NCHS Alphabetic Index. Index first, then the Tabular List.