DxCodebookFY2027 · Oct 1, 2026 – Sep 30, 2027

Block · Chapter 3

D80-D89 Certain disorders involving the immune mechanism (D80-D89)

Block D80-D89 groups 7 categories with 83 billable codes in FY2027.

Where it sits

  1. Chapter 3 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
  2. D80-D89 Certain disorders involving the immune mechanism (D80-D89)

Neighbouring blocks

Categories
7
Billable codes
83
CC codes
43
MCC codes
0
HCC V28 codes
35
New FY2027
0

Categories in D80-D89

  • D80

    Immunodeficiency with predominantly antibody defects

    Hypogammaglobulinemia → D80.1

    • 10 billable codes
    • 10 CC
    • 5 with HCC
  • D81

    Combined immunodeficiencies

    Nezelof's syndrome (pure alymphocytosis) → D81.4

    • 17 billable codes
    • 14 CC
    • 14 with HCC
  • D82

    Immunodeficiency associated with other major defects

    Di George's syndrome → D82.1

    • 7 billable codes
    • 2 CC
    • 2 with HCC
  • D83

    Common variable immunodeficiency

    SyndromeGood's → D83.8

    • 5 billable codes
    • 5 CC
    • 5 with HCC
  • D84

    Other immunodeficiencies

    Immunodeficiency → D84.9

    • 7 billable codes
    • 5 CC
    • 1 with HCC
  • D86

    Sarcoidosis

    Sarcoidosis → D86.9

    • 13 billable codes
    • 3 with HCC
  • D89

    Other disorders involving the immune mechanism, not elsewhere classified

    Paraproteinemia → D89.2

    • 24 billable codes
    • 7 CC
    • 5 with HCC

Index main terms

  • Immunodeficiency → D80, D81, D82, D83, D84 (41 entries)
  • Syndrome → D80, D81, D82, D83, D89 (32 entries)
  • Deficiency, deficient → D80, D81, D82, D84 (29 entries)
  • Disease, diseased → D80, D81, D82, D86, D89 (14 entries)
  • Sarcoidosis → D86 (13 entries)
  • Agammaglobulinemia (acquired (secondary)) (nonfamilial) → D80, D81 (11 entries)
  • Sarcoid → D86 (8 entries)
  • Absence (of) (organ or part) (complete or partial) → D80 (6 entries)
  • Disorder (of) → D86, D89 (6 entries)
  • Edema, edematous (infectious) (pitting) (toxic) → D84 (6 entries)
  • Activation → D89 (5 entries)
  • Graft-versus-host disease → D89 (4 entries)
  • Hypogammaglobulinemia → D80 (4 entries)
  • Defect, defective → D80, D84 (3 entries)
  • Hypergammaglobulinemia → D89 (3 entries)

+62 more main terms; the search box finds them by word.

Block instructions

Includes

  • defects in the complement system
  • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
  • sarcoidosis

Excludes1

  • autoimmune disease (systemic) NOS (M35.9) M35.9
  • functional disorders of polymorphonuclear neutrophils (D71-) D71

Excludes2

  • human immunodeficiency virus [HIV] disease (B20) B20

Notes that also apply

Chapter 3 instructions (Excludes2 9): printed on the chapter 3 page.