DxCodebookFY2027 · Oct 1, 2026 – Sep 30, 2027

Category · FY2027

E27 Other disorders of adrenal gland

  • Header · not billable

E27 is not billable. The category heads 9 billable codes in FY2027, grouped under 8 subdivisions.

Index → code

  • Hyperadrenalism → E27.5
  • Dysadrenocortism → E27.9
  • Addisonian crisis → E27.2

Where it sits

  1. Chapter 4 Endocrine, nutritional and metabolic diseases (E00-E89)
  2. E20-E35 Disorders of other endocrine glands (E20-E35)
  3. E27 Other disorders of adrenal gland
Billable codes
9
Subdivisions
8
CC / MCC codes
7 / 0
HCC V28 codes
1
New FY2027
0
Index entries
114

Codes in E27

  1. E27.0
    Other adrenocortical overactivity
    BillableCC
    Inclusion terms 2, Excludes1 1

    Inclusion terms

    • Overproduction of ACTH, not associated with Cushing's disease
    • Premature adrenarche

    Excludes1

    • Cushing's syndrome (E24.-) E24
  2. E27.1
    Primary adrenocortical insufficiency
    BillableCC51
    Inclusion terms 2, Excludes1 4

    Inclusion terms

    • Addison's disease
    • Autoimmune adrenalitis

    Excludes1

    • Addison only phenotype adrenoleukodystrophy (E71.528) E71.528
    • amyloidosis (E85.-) E85
    • tuberculous Addison's disease (A18.7) A18.7
    • Waterhouse-Friderichsen syndrome (A39.1) A39.1
  3. E27.2
    Addisonian crisis
    BillableCC
    Inclusion terms 2

    Inclusion terms

    • Adrenal crisis
    • Adrenocortical crisis
  4. E27.3
    Drug-induced adrenocortical insufficiency
    BillableCC
    Use additional code 1

    Use additional code

    • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) T36 T50
  5. E27.4
    Other and unspecified adrenocortical insufficiency
    Header
    Excludes1 2

    Excludes1

    • adrenoleukodystrophy [Addison-Schilder] (E71.528) E71.528
    • Waterhouse-Friderichsen syndrome (A39.1) A39.1
  6. E27.40
    Unspecified adrenocortical insufficiency
    BillableCC
    Inclusion terms 2

    Inclusion terms

    • Adrenocortical insufficiency NOS
    • Hypoaldosteronism
  7. E27.49
    Other adrenocortical insufficiency
    BillableCC
    Inclusion terms 2

    Inclusion terms

    • Adrenal hemorrhage
    • Adrenal infarction
  8. E27.5
    Adrenomedullary hyperfunction
    BillableCC
    Inclusion terms 2, Code also 4

    Inclusion terms

    • Adrenomedullary hyperplasia
    • Catecholamine hypersecretion

    Code also

    • , if applicable:
    • malignant pheochromocytoma (C74.1-) C74.1
    • pheochromocytoma (benign) (D35.0-) D35.0
    • secondary hypertension (I15.2) I15.2
  9. E27.8
    Other specified disorders of adrenal gland
    Billable
    Inclusion terms 1

    Inclusion terms

    • Abnormality of cortisol-binding globulin
  10. E27.9
    Disorder of adrenal gland, unspecified
    Billable

CC/MCC: as a secondary diagnosis, unless the principal diagnosis is on the code’s PDX exclusion list (MS-DRG v44 Appendix C; list on the code card).

Sources of each column.

Instructions

Notes that also apply

Block E20-E35 instructions (Excludes1 2): printed on the block page.

Chapter 4 instructions (Notes 1, Excludes1 1): printed on the chapter 4 page.

Index entries

  • Adrenarche, premature → E27.0
  • Schroeder's syndrome (endocrine hypertensive) → E27.0
  • Slocumb's syndrome → E27.0
  • Addisonian crisis → E27.2
  • Hypoadrenalism, hypoadrenia → E27.40
  • Hypoadrenocorticism → E27.40
  • Hypoaldosteronism → E27.40
  • Hyperadrenalism → E27.5
  • Adrenalitis, adrenitis → E27.8
  • Dysadrenocortism → E27.9
  • Dysadrenocortismhyperfunction → E27.0
  • Hyperadrenocorticismnot associated with Cushing's syndrome → E27.0
  • Hyperfunctionadrenal cortex, not associated with Cushing's syndrome → E27.0
  • HypersecretionACTH (not associated with Cushing's syndrome) → E27.0
  • Overactiveadrenal cortex NEC → E27.0
  • OverproductionACTH → E27.0
  • Prematureadrenarche → E27.0
  • Syndromeendocrine-hypertensive → E27.0
  • SyndromeSchroeder's → E27.0
  • SyndromeSlocumb's → E27.0
  • Syndromesuprarenal cortical → E27.0
  • Addison'sdisease (bronze) or syndrome → E27.1
  • Adrenalitis, adrenitisautoimmune → E27.1
  • Disease, diseasedbronze Addison's → E27.1
  • Hypoadrenalism, hypoadreniaprimary → E27.1
  • Hypoadrenocorticismprimary → E27.1
  • Melanosisaddisonian → E27.1
  • Melanosisadrenal → E27.1
  • Melanosissuprarenal → E27.1
  • Melasmaadrenal (gland) → E27.1
  • Melasmasuprarenal (gland) → E27.1
  • Collapseadrenal → E27.2
  • Crisisaddisonian → E27.2
  • Crisisadrenal (cortical) → E27.2
  • Shockadrenal (cortical) (Addisonian) → E27.2
  • Deficiency, deficientcorticoadrenal → E27.40
  • Hypofunctionadrenocortical → E27.40
  • Hypofunctioncorticoadrenal NEC → E27.40
  • Insufficiency, insufficientadrenal (gland) → E27.40
  • Insufficiency, insufficientadrenocortical → E27.40

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