DxCodebookFY2027 · Oct 1, 2026 – Sep 30, 2027

Category · FY2027

E85 Amyloidosis

  • Header · not billable

E85 is not billable. The category heads 9 billable codes in FY2027, grouped under 7 subdivisions.

Index → code

  • Paramyloidosis → E85.89
  • Amyloid heart (disease) → E85.4 [I43]
  • Amyloidosis (generalized) (primary) → E85.9

Where it sits

  1. Chapter 4 Endocrine, nutritional and metabolic diseases (E00-E89)
  2. E70-E88 Metabolic disorders (E70-E88)
  3. E85 Amyloidosis
Billable codes
9
Subdivisions
7
CC / MCC codes
9 / 0
HCC V28 codes
9
New FY2027
0
Index entries
62

Codes in E85

  1. E85.0
    Non-neuropathic heredofamilial amyloidosis
    BillableCC50
    Inclusion terms 1, Excludes2 1, Code also 2

    Inclusion terms

    • Hereditary amyloid nephropathy

    Excludes2

    • Transthyretin-related (ATTR) familial amyloid cardiomyopathy (E85.4) E85.4

    Code also

    • associated disorders, such as:
    • autoinflammatory syndromes (M04.-) M04
  2. E85.1
    Neuropathic heredofamilial amyloidosis
    BillableCC50
    Inclusion terms 2

    Inclusion terms

    • Amyloid polyneuropathy (Portuguese)
    • Transthyretin-related (ATTR) familial amyloid polyneuropathy
  3. E85.2
    Heredofamilial amyloidosis, unspecified
    BillableCC50
  4. E85.3
    Secondary systemic amyloidosis
    BillableCC50
    Inclusion terms 1

    Inclusion terms

    • Hemodialysis-associated amyloidosis
  5. E85.4
    Organ-limited amyloidosis
    BillableCC50
    Inclusion terms 2

    Inclusion terms

    • Localized amyloidosis
    • Transthyretin-related (ATTR) familial amyloid cardiomyopathy
  6. E85.8
    Other amyloidosis
    Header
  7. E85.81
    Light chain (AL) amyloidosis
    BillableCC50
  8. E85.82
    Wild-type transthyretin-related (ATTR) amyloidosis
    BillableCC50
    Inclusion terms 1

    Inclusion terms

    • Senile systemic amyloidosis (SSA)
  9. E85.89
    Other amyloidosis
    BillableCC50
  10. E85.9
    Amyloidosis, unspecified
    BillableCC50

CC/MCC: as a secondary diagnosis, unless the principal diagnosis is on the code’s PDX exclusion list (MS-DRG v44 Appendix C; list on the code card).

Sources of each column.

Instructions

At E85

Excludes2

  • Alzheimer's disease (G30.0-) G30.0

Notes that also apply

Block E70-E88 instructions (Excludes1 5, Excludes2 1): printed on the block page.

Chapter 4 instructions (Notes 1, Excludes1 1): printed on the chapter 4 page.

Index entries

  • Amyloid heart (disease) → E85.4 [I43]
  • Paramyloidosis → E85.89
  • Amyloidosis (generalized) (primary) → E85.9
  • Amyloidosis (generalized) (primary)non-neuropathic heredofamilial → E85.0
  • Nephropathyamyloid, hereditary → E85.0
  • Peritonitis (adhesive) (bacterial) (fibrinous) (hemorrhagic) (idiopathic) (localized) (perforative) (primary) (with adhesions) (with effusion)paroxysmal, familial → E85.0
  • Peritonitis (adhesive) (bacterial) (fibrinous) (hemorrhagic) (idiopathic) (localized) (perforative) (primary) (with adhesions) (with effusion)periodic, familial → E85.0
  • Polyserositisperiodic, familial → E85.0
  • Amyloidosis (generalized) (primary)neuropathic heredofamilial → E85.1
  • Amyloidosis (generalized) (primary)Portuguese → E85.1
  • Polyneuropathy (peripheral)amyloid (Portuguese) → E85.1 [G63]
  • Amyloidosis (generalized) (primary)familial → E85.2
  • Amyloidosis (generalized) (primary)genetic → E85.2
  • Amyloidosis (generalized) (primary)hemodialysis-associated → E85.3
  • Amyloidosis (generalized) (primary)secondary systemic → E85.3
  • Amyloidosis (generalized) (primary)with lung involvement → E85.4 [J99]
  • Amyloidosis (generalized) (primary)heart → E85.4 [I43]
  • Amyloidosis (generalized) (primary)liver → E85.4 [K77]
  • Amyloidosis (generalized) (primary)localized → E85.4
  • Amyloidosis (generalized) (primary)organ limited → E85.4
  • Amyloidosis (generalized) (primary)pulmonary → E85.4 [J99]
  • Amyloidosis (generalized) (primary)skin (lichen) (macular) → E85.4 [L99]
  • Amyloidosis (generalized) (primary)subglottic → E85.4 [J99]
  • Cardiomyopathy (familial) (idiopathic)amyloid → E85.4 [I43]
  • Cardiomyopathy (familial) (idiopathic)transthyretin-related (ATTR) familial amyloid → E85.4
  • Degeneration, degenerativeintestine, amyloid → E85.4
  • Lichenamyloidosis → E85.4 [L99]
  • Nephritis, nephritic (albuminuric) (azotemic) (congenital) (disseminated) (epithelial) (familial) (focal) (granulomatous) (hemorrhagic) (infantile) (nonsuppurative, excretory) (uremic)amyloid → E85.4 [N08]
  • Neuritis (rheumatoid)amyloid, any site → E85.4 [G63]
  • Amyloidosis (generalized) (primary)light chain (AL) → E85.81
  • Amyloidosis (generalized) (primary)senile systemic (SSA) → E85.82
  • Amyloidosis (generalized) (primary)wild-type transthyretin-related (ATTR) → E85.82
  • Amyloidosis (generalized) (primary)specified NEC → E85.89
  • Degeneration, degenerativeamyloid → E85.9
  • Myopathyin (due to)amyloidosis → E85.0 [G73.7]
  • Peritonitis (adhesive) (bacterial) (fibrinous) (hemorrhagic) (idiopathic) (localized) (perforative) (primary) (with adhesions) (with effusion)paroxysmal, familialbenign → E85.0
  • Polyneuropathy (peripheral)amyloid (Portuguese)transthyretin-related (ATTR) familial → E85.1 [G63]
  • Polyneuropathy (peripheral)in (due to)amyloidosis, familial (Portuguese) → E85.1 [G63]
  • Polyneuropathy (peripheral)in (due to)transthyretin-related (ATTR) familial amyloid → E85.1
  • Angiopathia, angiopathycerebralamyloid → E85.4 [I68.0]

22 more, longer entries are not listed; the search box finds them by word.

NCHS Alphabetic Index. Index first, then the Tabular List.

Hierarchy