DxCodebookFY2027 · Oct 1, 2026 – Sep 30, 2027

Category · FY2027

E78 Disorders of lipoprotein metabolism and other lipidemias

  • Header · not billable

E78 is not billable. The category heads 18 billable codes in FY2027, grouped under 10 subdivisions.

ICD-10 code by name

What is the ICD-10 code for hyperlipidemia, unspecified?
Hyperlipidemia ICD-10 code: E78.5 Hyperlipidemia, unspecified. Search ICD-10 for hyperlipidemia
What is the ICD-10 code for mixed hyperlipidemia?
Mixed hyperlipidemia ICD-10 code: E78.2 Mixed hyperlipidemia. Search ICD-10 for mixed hyperlipidemia
What is the ICD-10 code for other hyperlipidemia?
Other hyperlipidemia ICD-10 code: E78.49 Other hyperlipidemia. Search ICD-10 for other hyperlipidemia

Where it sits

  1. Chapter 4 Endocrine, nutritional and metabolic diseases (E00-E89)
  2. E70-E88 Metabolic disorders (E70-E88)
  3. E78 Disorders of lipoprotein metabolism and other lipidemias
Billable codes
18
Subdivisions
10
CC / MCC codes
2 / 0
HCC V28 codes
0
New FY2027
0
Index entries
95

Codes in E78

  1. E78.0
    Pure hypercholesterolemia
    Header
  2. E78.00
    Pure hypercholesterolemia, unspecified
    Billable
    Inclusion terms 4

    Inclusion terms

    • Fredrickson's hyperlipoproteinemia, type IIa
    • Hyperbetalipoproteinemia
    • Low-density-lipoprotein-type [LDL] hyperlipoproteinemia
    • (Pure) hypercholesterolemia NOS
  3. E78.01
    Familial hypercholesterolemia
    Header
  4. E78.010
    Homozygous familial hypercholesterolemia [HoFH]
    Billable
  5. E78.011
    Heterozygous familial hypercholesterolemia [HeFH]
    Billable
  6. E78.019
    Familial hypercholesterolemia, unspecified
    Billable
    Inclusion terms 1

    Inclusion terms

    • Familial hypercholesterolemia NOS
  7. E78.1
    Pure hyperglyceridemia 1 billable code
    Billable
  8. E78.2
    Mixed hyperlipidemia 1 billable code
    Billable
  9. E78.3
    Hyperchylomicronemia
    Billable
    Inclusion terms 4

    Inclusion terms

    • Chylomicron retention disease
    • Fredrickson's hyperlipoproteinemia, type I or V
    • Hyperlipidemia, group D
    • Mixed hyperglyceridemia
  10. E78.4
    Other hyperlipidemia
    Header
  11. E78.41
    Elevated Lipoprotein(a)
    Billable
    Inclusion terms 1

    Inclusion terms

    • Elevated Lp(a)
  12. E78.49
    Other hyperlipidemia 1 billable code
    Billable
  13. E78.5
    Hyperlipidemia, unspecified 1 billable code
    Billable
  14. E78.6
    Lipoprotein deficiency
    Billable
    Inclusion terms 7

    Inclusion terms

    • Abetalipoproteinemia
    • Depressed HDL cholesterol
    • High-density lipoprotein deficiency
    • Hypoalphalipoproteinemia
    • Hypobetalipoproteinemia (familial)
    • Lecithin cholesterol acyltransferase deficiency
    • Tangier disease
  15. E78.7
    Disorders of bile acid and cholesterol metabolism
    Header
    Excludes1 1

    Excludes1

    • Niemann-Pick disease type C (E75.242) E75.242
  16. E78.70
    Disorder of bile acid and cholesterol metabolism, unspecified
    Billable
  17. E78.71
    Barth syndrome
    BillableCC
  18. E78.72
    Smith-Lemli-Opitz syndrome
    BillableCC
  19. E78.79
    Other disorders of bile acid and cholesterol metabolism
    Billable
  20. E78.8
    Other disorders of lipoprotein metabolism
    Header
  21. E78.81
    Lipoid dermatoarthritis
    Billable
  22. E78.89
    Other lipoprotein metabolism disorders
    Billable
  23. E78.9
    Disorder of lipoprotein metabolism, unspecified
    Billable

CC/MCC: as a secondary diagnosis, unless the principal diagnosis is on the code’s PDX exclusion list (MS-DRG v44 Appendix C; list on the code card).

Sources of each column.

Instructions

At E78

Excludes1

Notes that also apply

Block E70-E88 instructions (Excludes1 5, Excludes2 1): printed on the block page.

Chapter 4 instructions (Notes 1, Excludes1 1): printed on the chapter 4 page.

Index entries

  • Cholesteremia → E78.00
  • Cholesterolemia (essential) (pure) → E78.00
  • Hyperbetalipoproteinemia (familial) → E78.00
  • Hypercholesterolemia (essential) (primary) (pure) → E78.00
  • Low-density-lipoprotein-type (LDL) hyperlipoproteinemia → E78.00
  • HoFH (homozygous familial hypercholesterolemia) → E78.010
  • HeFH (heterozygous familial hypercholesterolemia) → E78.011
  • Bürger-Grütz disease or syndrome → E78.3
  • Chylomicronemia (fasting) (with hyperprebetalipoproteinemia) → E78.3
  • Hyperchylomicronemia (familial) (primary) → E78.3
  • Abetalipoproteinemia → E78.6
  • Acanthocytosis → E78.6
  • Analphalipoproteinemia → E78.6
  • Bassen-Kornzweig disease or syndrome → E78.6
  • Hypoalphalipoproteinemia → E78.6
  • Hypobetalipoproteinemia (familial) → E78.6
  • Hypolipoproteinemia (alpha) (beta) → E78.6
  • Tangier disease → E78.6
  • Barth syndrome → E78.71
  • Smith-Lemli-Opitz syndrome → E78.72
  • Dermatoarthritis, lipoid → E78.81
  • Lipogranulomatosis → E78.89
  • Urbach's lipoid proteinosis → E78.89
  • Urbach-Wiethe disease → E78.89
  • Lipoprotein metabolism disorder → E78.9
  • Osteochondrodystrophy → E78.9
  • Cholesterolelevated (high) → E78.00
  • Elevated, elevationcholesterol → E78.00
  • Frederickson's hyperlipoproteinemia, typeIIA → E78.00
  • Highcholesterol → E78.00
  • Hyperlipoproteinemialow-density-lipoprotein-type (LDL) → E78.00
  • Xanthoma (s), xanthomatosis (primary) (familial) (hereditary)hypercholesterinemic → E78.00
  • Xanthoma (s), xanthomatosis (primary) (familial) (hereditary)hypercholesterolemic → E78.00
  • Cholesterolemia (essential) (pure)familial → E78.019
  • Cholesterolemia (essential) (pure)hereditary → E78.019
  • Hypercholesterolemia (essential) (primary) (pure)familial → E78.019
  • Hypercholesterolemia (essential) (primary) (pure)hereditary → E78.019
  • Disease, diseasedBürger-Grütz (essential familial hyperlipemia) → E78.3
  • Disease, diseasedchylomicron retention → E78.3
  • Frederickson's hyperlipoproteinemia, typeI and V → E78.3

55 more, longer entries are not listed; the search box finds them by word.

NCHS Alphabetic Index. Index first, then the Tabular List.

Hierarchy