DxCodebookFY2027 · Oct 1, 2026 – Sep 30, 2027

E78.2 diagnosis code · Billable code · FY2027

E78.2 Mixed hyperlipidemia

  • Billable
  • Not CC/MCC
  • POA reported

E78.2 ICD-10 code: a billable diagnosis code in FY2027, one of 18 billable codes in category E78.

Where it sits

  1. Chapter 4 Endocrine, nutritional and metabolic diseases (E00-E89)
  2. E70-E88 Metabolic disorders (E70-E88)
  3. E78 Disorders of lipoprotein metabolism and other lipidemias
  4. E78.2 Mixed hyperlipidemia
CC / MCC
Neither
MS-DRG
642
HCC V28
–
POA
Reported
Code Editor
–
Index entries
33

Instructions

At E78.2

Inclusion terms

  • Broad- or floating-betalipoproteinemia
  • Combined hyperlipidemia NOS
  • Elevated cholesterol with elevated triglycerides NEC
  • Fredrickson's hyperlipoproteinemia, type IIb or III
  • Hyperbetalipoproteinemia with prebetalipoproteinemia
  • Hypercholesteremia with endogenous hyperglyceridemia
  • Hyperlipidemia, group C
  • Tubo-eruptive xanthoma
  • Xanthoma tuberosum

Excludes1

  • cerebrotendinous cholesterosis [van Bogaert-Scherer- Epstein] (E75.5) E75.5
  • familial combined hyperlipidemia (E78.49) E78.49

Notes that also apply

Excludes1 from E78

Block E70-E88 instructions (Excludes1 5, Excludes2 1): printed on the block page.

Chapter 4 instructions (Notes 1, Excludes1 1): printed on the chapter 4 page.

Index entries

  • Betalipoproteinemia, broad or floating → E78.2
  • Broad- or floating-betalipoproteinemia → E78.2
  • Dysbetalipoproteinemia (familial) → E78.2
  • Xanthelasmatosis (essential) → E78.2
  • Xanthoma (s), xanthomatosis (primary) (familial) (hereditary) → E78.2
  • Broadbeta disease → E78.2
  • Frederickson's hyperlipoproteinemia, typeIIB and III → E78.2
  • Hyperbetalipoproteinemia (familial)with prebetalipoproteinemia → E78.2
  • Hypercholesterolemia (essential) (primary) (pure)with hyperglyceridemia, endogenous → E78.2
  • Hyperlipemia, hyperlipidemiacombined → E78.2
  • Hyperlipemia, hyperlipidemiamixed → E78.2
  • Lipoproteinemiabroad-beta → E78.2
  • Lipoproteinemiafloating-beta → E78.2
  • Xanthoma (s), xanthomatosis (primary) (familial) (hereditary)disseminatum (skin) → E78.2
  • Xanthoma (s), xanthomatosis (primary) (familial) (hereditary)eruptive → E78.2
  • Xanthoma (s), xanthomatosis (primary) (familial) (hereditary)multiple (skin) → E78.2
  • Xanthoma (s), xanthomatosis (primary) (familial) (hereditary)tubo-eruptive → E78.2
  • Xanthoma (s), xanthomatosis (primary) (familial) (hereditary)tuberosum → E78.2
  • Xanthoma (s), xanthomatosis (primary) (familial) (hereditary)tuberous → E78.2
  • Cholesterolelevated (high)with elevated (high) triglycerides → E78.2
  • Cirrhosis, cirrhotic (hepatic) (liver)due toxanthomatosis → E78.2
  • Cirrhosis, cirrhotic (hepatic) (liver)xanthomatous (biliary)due to xanthomatosis (familial) (metabolic) (primary) → E78.2
  • Disease, diseasedbroadbeta → E78.2
  • Elevated, elevationcholesterolwith high triglycerides → E78.2
  • Elevated, elevationtriglycerideswith high cholesterol → E78.2
  • Highcholesterolwith high triglycerides → E78.2
  • Hightriglycerideswith high cholesterol → E78.2
  • Hyperlipemia, hyperlipidemiagroupC → E78.2
  • HyperlipoproteinemiaFredrickson's typeIIb → E78.2
  • HyperlipoproteinemiaFredrickson's typeIII → E78.2
  • Findings, abnormal, inconclusive, without diagnosischolesterolhighwith high triglycerides → E78.2
  • Findings, abnormal, inconclusive, without diagnosistriglycerideshighwith high cholesterol → E78.2
  • Xanthoma (s), xanthomatosis (primary) (familial) (hereditary)withhyperlipoproteinemiaType III → E78.2

NCHS Alphabetic Index. Index first, then the Tabular List.

Medicare grouping and edits

CMS files for E78.2
CC / MCCNeither
Appendix BMDC 10 Endocrine, Nutritional and Metabolic Diseases and Disorders, MS-DRG 642 (Inborn and Other Disorders of Metabolism…)
Code Editor–
POAReported
HCC V28–

CMS: MS-DRG v44 (Appendix B, C), MCE v44, POA list FY2027, 2027 Initial ICD-10-CM Mappings. What the rows mean.

Hierarchy