DxCodebookFY2027 · Oct 1, 2026 – Sep 30, 2027

Category · FY2027

Z15 Genetic susceptibility to disease

  • Header · not billable

Z15 is not billable. The category heads 14 billable codes in FY2027, grouped under 5 subdivisions.

Index → code

  • Susceptibility to disease, genetic → Z15.89
  • Geneticsusceptibility to disease NEC → Z15.89
  • Family, familialLi-Fraumeni (syndrome) → Z15.01

Where it sits

  1. Chapter 21 Factors influencing health status and contact with health services (Z00-Z99)
  2. Z14-Z15 Genetic carrier and genetic susceptibility to disease (Z14-Z15)
  3. Z15 Genetic susceptibility to disease
Billable codes
14
Subdivisions
5
CC / MCC codes
0 / 0
HCC V28 codes
0
New FY2027
0
Index entries
29

Codes in Z15

  1. Z15.0
    Genetic susceptibility to malignant neoplasm
    Header
    Code first 1, Use additional code 1

    Code first

    • , if applicable, any current malignant neoplasm (C00-C75, C81-C96) C00 C75 C81 C96

    Use additional code

    • code, if applicable, for any personal history of malignant neoplasm (Z85.-) Z85
  2. Z15.01
    Genetic susceptibility to malignant neoplasm of breast
    BillableExempt
  3. Z15.02
    Genetic susceptibility to malignant neoplasm of ovary
    BillableExempt
  4. Z15.03
    Genetic susceptibility to malignant neoplasm of prostate
    BillableExempt
  5. Z15.04
    Genetic susceptibility to malignant neoplasm of endometrium
    BillableExempt
  6. Z15.05
    Genetic susceptibility to malignant neoplasm of fallopian tube(s)
    BillableExempt
  7. Z15.06
    Genetic susceptibility to malignant neoplasm of digestive system
    Header
  8. Z15.060
    Genetic susceptibility to colorectal cancer
    BillableExempt
  9. Z15.068
    Genetic susceptibility to other malignant neoplasm of digestive system
    BillableExempt
    Inclusion terms 4

    Inclusion terms

    • Genetic susceptibility to biliary tract cancer
    • Genetic susceptibility to gastric cancer
    • Genetic susceptibility to pancreatic cancer
    • Genetic susceptibility to small bowel cancer
  10. Z15.07
    Genetic susceptibility to malignant neoplasm of urinary tract
    BillableExempt
  11. Z15.09
    Genetic susceptibility to other malignant neoplasm
    BillableExempt
  12. Z15.1
    Genetic susceptibility to epilepsy and neurodevelopmental disorders
    BillableExempt
    Code also 8

    Code also

    • , if applicable, related disorders such as:
    • developmental and epileptic encephalopathy (G93.45) G93.45
    • developmental disorder of speech and language (F80.-) F80
    • developmental disorders of scholastic skills (F81.-) F81
    • epilepsy, by specific type (G40.-) G40
    • intellectual disabilities (F70-F79) F70 F79
    • other neurodevelopmental disorder (F88) F88
    • pervasive developmental disorders (F84.-) F84
  13. Z15.2
    Genetic susceptibility to obesity
    BillableExempt
    Use additional code 1, Code also 3

    Use additional code

    • code to identify body mass index (BMI), if known (Z68.-) Z68

    Code also

    • , if applicable, any associated manifestations, such as:
    • other obesity (E66.8-) E66.8
    • polyphagia (R63.2) R63.2
  14. Z15.3
    Genetic susceptibility to kidney disease
    BillableExempt
    Code also 1

    Code also

    • , if applicable, hypertension (I10-I1A) I10 I1A
  15. Z15.8
    Genetic susceptibility to other disease
    Header
  16. Z15.81
    Genetic susceptibility to multiple endocrine neoplasia [MEN]
    BillableExempt
    Excludes1 1

    Excludes1

    • multiple endocrine neoplasia [MEN] syndromes (E31.2-) E31.2
  17. Z15.89
    Genetic susceptibility to other disease
    BillableExempt

Sources of each column.

Instructions

At Z15

Includes

  • confirmed abnormal gene

Excludes1

  • chromosomal anomalies (Q90-Q99) Q90 Q99

Use additional code

  • code, if applicable, for any associated family history of the disease (Z80-Z84) Z80 Z84

Notes that also apply

Chapter 21 instructions (Notes 3): printed on the chapter 21 page.

Index entries

  • Susceptibility to disease, genetic → Z15.89
  • Family, familialLi-Fraumeni (syndrome) → Z15.01
  • Susceptibility to disease, geneticmalignant neoplasm → Z15.09
  • Susceptibility to disease, geneticmultiple endocrine neoplasia → Z15.81
  • Geneticsusceptibility to disease NEC → Z15.89
  • Susceptibility to disease, geneticmalignant neoplasmbreast → Z15.01
  • Susceptibility to disease, geneticmalignant neoplasmovary → Z15.02
  • Susceptibility to disease, geneticmalignant neoplasmprostate → Z15.03
  • Susceptibility to disease, geneticmalignant neoplasmendometrium → Z15.04
  • Susceptibility to disease, geneticmalignant neoplasmfallopian tube(s) → Z15.05
  • Geneticsusceptibility to disease NECmalignant neoplasm → Z15.09
  • Susceptibility to disease, geneticmalignant neoplasmspecified NEC → Z15.09
  • Geneticsusceptibility to disease NECepilepsy → Z15.1
  • Geneticsusceptibility to disease NECneurodevelopmental disorders → Z15.1
  • Geneticsusceptibility to disease NECobesity → Z15.2
  • Geneticsusceptibility to disease NECkidney disease → Z15.3
  • Geneticsusceptibility to disease NECmultiple endocrine neoplasia → Z15.81
  • Geneticsusceptibility to disease NECmalignant neoplasmbreast → Z15.01
  • Geneticsusceptibility to disease NECmalignant neoplasmovary → Z15.02
  • Geneticsusceptibility to disease NECmalignant neoplasmprostate → Z15.03
  • Geneticsusceptibility to disease NECmalignant neoplasmendometrium → Z15.04
  • Geneticsusceptibility to disease NECmalignant neoplasmfallopian tube(s) → Z15.05
  • Geneticsusceptibility to disease NECmalignant neoplasmcolorectal → Z15.060
  • Geneticsusceptibility to disease NECmalignant neoplasmbiliary tract → Z15.068
  • Geneticsusceptibility to disease NECmalignant neoplasmdigestive system NEC → Z15.068
  • Geneticsusceptibility to disease NECmalignant neoplasmgastric → Z15.068
  • Geneticsusceptibility to disease NECmalignant neoplasmpancreas → Z15.068
  • Geneticsusceptibility to disease NECmalignant neoplasmurinary tract → Z15.07
  • Geneticsusceptibility to disease NECmalignant neoplasmspecified NEC → Z15.09

NCHS Alphabetic Index. Index first, then the Tabular List.

Hierarchy