DxCodebookFY2027 · Oct 1, 2026 – Sep 30, 2027

Category · FY2027

D55 Anemia due to enzyme disorders

  • Header · not billable

D55 is not billable. The category heads 7 billable codes in FY2027, grouped under 6 subdivisions.

Index → code

  • Favism (anemia) → D55.0
  • Toxicityfava bean → D55.0
  • Poisoning (acute)fava bean → D55.0

Where it sits

  1. Chapter 3 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
  2. D55-D59 Hemolytic anemias (D55-D59)
  3. D55 Anemia due to enzyme disorders
Billable codes
7
Subdivisions
6
CC / MCC codes
0 / 0
HCC V28 codes
0
New FY2027
0
Index entries
52

Codes in D55

  1. D55.0
    Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
    Billable
    Inclusion terms 2, Excludes1 1

    Inclusion terms

    • Favism
    • G6PD deficiency anemia

    Excludes1

    • glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia (D75.A) D75.A
  2. D55.1
    Anemia due to other disorders of glutathione metabolism
    Billable
    Inclusion terms 2

    Inclusion terms

    • Anemia (due to) enzyme deficiencies, except G6PD, related to the hexose monophosphate [HMP] shunt pathway
    • Anemia (due to) hemolytic nonspherocytic (hereditary), type I
  3. D55.2
    Anemia due to disorders of glycolytic enzymes
    Header
    Excludes1 1

    Excludes1

    • disorders of glycolysis not associated with anemia (E74.81-) E74.81
  4. D55.21
    Anemia due to pyruvate kinase deficiency
    Billable
    Inclusion terms 2

    Inclusion terms

    • PK deficiency anemia
    • Pyruvate kinase deficiency anemia
  5. D55.29
    Anemia due to other disorders of glycolytic enzymes
    Billable
    Inclusion terms 2

    Inclusion terms

    • Hexokinase deficiency anemia
    • Triose-phosphate isomerase deficiency anemia
  6. D55.3
    Anemia due to disorders of nucleotide metabolism
    Billable
  7. D55.8
    Other anemias due to enzyme disorders
    Billable
  8. D55.9
    Anemia due to enzyme disorder, unspecified
    Billable

Sources of each column.

Instructions

At D55

Excludes1

  • drug-induced enzyme deficiency anemia (D59.2) D59.2

Notes that also apply

Chapter 3 instructions (Excludes2 9): printed on the chapter 3 page.

Index entries

  • Favism (anemia) → D55.0
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)Baghdad spring → D55.0
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)favism → D55.0
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)glucose-6-phosphate dehydrogenase (G6PD) deficiency → D55.0
  • Poisoning (acute)fava bean → D55.0
  • Toxicityfava bean → D55.0
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)erythrocytic glutathione deficiency → D55.1
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)glutathione-reductase deficiency → D55.1
  • Disorder (of)pentose phosphate pathway with anemia → D55.1
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)pyruvate kinase deficiency → D55.21
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)hexokinase deficiency → D55.29
  • Disorder (of)anaerobic glycolysis with anemia → D55.29
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencyglucose-6-phosphate dehydrogenase → D55.0
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencyG6PD → D55.0
  • Deficiency, deficientglucose-6-phosphate dehydrogenaseanemia → D55.0
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiency6 phosphogluconate dehydrogenase → D55.1
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiency6-PGD → D55.1
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencyerythrocytic glutathione → D55.1
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencyG SH → D55.1
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencyGGS-R → D55.1
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencyglutathione reductase → D55.1
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencyPK → D55.21
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencypyruvate kinase → D55.21
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiency2, 3 diphosphoglycurate mutase → D55.29
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiency2, 3 PG → D55.29
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencyglyceraldehyde phosphate dehydrogenase → D55.29
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencyhexokinase → D55.29
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencyphosphofructo-aldolase → D55.29
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencyphosphoglycerate kinase → D55.29
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencytriose-phosphate isomerase → D55.29
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencyenzyme → D55.9
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)due to (in) (with)enzyme disorder → D55.9
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencyenzymeglucose-6-phosphate dehydrogenase (G6PD) → D55.0
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)with (due to) (in)disorder ofpentose phosphate pathway → D55.1
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencyenzymerelated to hexose monophosphate (HMP) shunt pathway NEC → D55.1
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)due to (in) (with)disorder ofglutathione metabolism → D55.1
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)with (due to) (in)disorder ofanaerobic glycolysis → D55.29
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencyenzymeglycolytic → D55.29
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)deficiencyenzymenucleotide metabolism → D55.3
  • Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)due to (in) (with)disorder ofnucleotide metabolism → D55.3

12 more, longer entries are not listed; the search box finds them by word.

NCHS Alphabetic Index. Index first, then the Tabular List.

Hierarchy